Evidência da ação antiparasitária da azitromicina na infecção experimental de camundongos pelo Plasmodium berghei / Experimental infection in mice by Plasmodium berghei: an evidence of antiparasitic action of azithromycin
Rev. Soc. Bras. Med. Trop
;
34(2): 203-205, mar.-abr. 2001. ilus
Article
in Portuguese
| LILACS
| ID: lil-462020
ABSTRACT
Infections of Plasmodium berghei in mice was stopped by azithromycin which was administered orally in dosages of 100mg/kg, for 28 days. This antibiotic was given since the same day that the animals were infected. The outcome suggests the necessity of more investigations on this antiparasitic activity.
RESUMO
A azitromicina debelou a infecção experimental de camundongos pelo Plasmodium berghei quando administrada, pela via oral e durante 28 dias, na dose de 100mg/kg, iniciada no mesmo dia em que os animais foram infectados. Mediante uso de 10mg/kg houve insucesso. Os resultados obtidos suscitam investigações complementares sobre a referida atividade antiparasitária desse medicamento.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Plasmodium berghei
/
Azithromycin
/
Malaria
/
Anti-Bacterial Agents
Limits:
Animals
Language:
Portuguese
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2001
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto de Medicina Tropical de São Paulo/BR
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