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Estudo da capacidade alcalinizante de tampões metabolizáveis em bovinos sadios / The alkalinizing effects of different metabolizable buffers in healthy steers
Leal, M. L. R; Mori, C. S; Ortolani, E. L.
  • Leal, M. L. R; Universidade Federal de Santa Maria. Santa Maria. BR
  • Mori, C. S; USP. Faculdade de Medicina Veterinária e Zootecnia. São Paulo. BR
  • Ortolani, E. L; USP. Faculdade de Medicina Veterinária e Zootecnia. São Paulo. BR
Arq. bras. med. vet. zootec ; 59(4): 965-970, ago. 2007. ilus
Article in Portuguese | LILACS | ID: lil-462194
RESUMO
Seis novilhos mestiços, com cerca de 250kg e um ano de idade, foram infundidos, no decorrer de quatro horas, com cinco litros de diferentes soluções isotônicas de sais sódicos, com 150mM/l de bicarbonato, acetato, propionato, lactato L, lactato racêmico e cloreto (controle), em delineamento em quadrado latino (6x6). Análises hemogasométricas e do pH urinário foram determinadas no decorrer da infusão - zero, primeira e quatro horas - e após o seu término, na oitava hora. O pH do sangue foi maior nos animais infundidos com os tampões que nos infundidos com cloreto; teores mais elevados de bicarbonato e de excesso de ácido-base sanguíneos foram obtidos na quarta e oitava hora nos infundidos com bicarbonato e lactato; o mesmo ocorreu com a pressão de CO2 na oitava hora. Os resultados indicam que os tratamentos com Bicarbonato e lactato proporcionam acúmulo de tampões no sangue e geram discreta alcalose metabólica, compensada organicamente por leve retenção de CO2. a infusão com bicarbonato de sódio causa elevação do pH urinário
ABSTRACT
Six healthy crossbred yearling 250kg steers were infused intravenously, during four hours, with five liters of each of the six different isotonic solutions of sodium salts containing 150 mMol/l of the bicarbonate, acetate, propionate, L-lactate, D and L-lactate and chloride in a 6 x 6 latin square experimental design. Blood was collected from the jugular vein, anaerobically, for blood gas analysis, samples were obtained at different times throughout the infusion (zero, 1st, 4th and 8th h ). Urine was collect for determining the pH at the same schedule. Higher blood pH was found in cattle infused with all buffers than the chloride infused animals; higher level of blood bicarbonate and base excess were obtained at 4th and 8th h with bicarbonate and L-lactate, as well as with pCO2 at the 8th h. These results show that treatments with B and L lead to a slight accumulation of buffers in the blood, and generate a discrete metabolic alkalosis compensated organically by a small retention of CO2. Best alkalinizing effects are obtained by bicarbonate and L-lactato infusions. Bicarbonate infusions causes a high urinary pH
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Propionates / Acidosis / Bicarbonates / Buffers / Cattle / Alkalinization / Lactates / Acetates Limits: Animals Language: Portuguese Journal: Arq. bras. med. vet. zootec Journal subject: Veterinary Medicine Year: 2007 Type: Article Affiliation country: Brazil Institution/Affiliation country: USP/BR / Universidade Federal de Santa Maria/BR

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Full text: Available Index: LILACS (Americas) Main subject: Propionates / Acidosis / Bicarbonates / Buffers / Cattle / Alkalinization / Lactates / Acetates Limits: Animals Language: Portuguese Journal: Arq. bras. med. vet. zootec Journal subject: Veterinary Medicine Year: 2007 Type: Article Affiliation country: Brazil Institution/Affiliation country: USP/BR / Universidade Federal de Santa Maria/BR