Analysis and chromosomal mapping of Leishmania (Leishmania) amazonensis amastigote expressed sequence tags
Mem. Inst. Oswaldo Cruz
;
102(6): 707-711, Sept. 2007. tab
Article
in English
| LILACS
| ID: lil-463476
ABSTRACT
The characterization of expressed sequence tags (ESTs) generated from a cDNA library of Leishmania (Leishmania) amazonensis amastigotes is described. The sequencing of 93 clones generated new L. (L.) amazonensis ESTs from which 32 percent are not related to any other sequences in database and 68 percent presented significant similarities to known genes. The chromosome localization of some L. (L.) amazonensis ESTs was also determined in L. (L.) amazonensis and L. (L.) major. The characterization of these ESTs is suitable for the genome physical mapping, as well as for the identification of genes encoding cysteine proteinases implicated with protective immune responses in leishmaniasis.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cysteine Endopeptidases
/
DNA, Protozoan
/
Chromosome Mapping
/
Expressed Sequence Tags
/
Leishmania
Limits:
Animals
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de São Paulo/BR
Similar
MEDLINE
...
LILACS
LIS