Detection of enteroviral sequence in endomyocardial tissues from patients with cardiac diseases in northern Brazil
Rev. Soc. Bras. Med. Trop
;
31(5): 487-490, set.-out. 1998. ilus
Article
in English
| LILACS
| ID: lil-463599
RESUMO
No presente trabalho, são mostrados resultados de um estudo piloto direcionado à detecção de seqüências de enterovirus em tecido cardíaco obtido a partir de biópsias endomiocárdicas de pacientes com doenças cardíacas na região Amazônica. Seis amostras coletadas de três pacientes foram analisadas por RT-PCR obtendo-se três espécimes positivos e três negativos. Esses achados preliminares sugerem a participação dos enterovirus na etiologia de doenças cardíacas, principalmente miocardites, e justificam estudos mais amplos nesse assunto.
ABSTRACT
In the present report we describe the results from a pilot study aimed at detecting enterovirus sequence in cardiac tissues, obtained through endomyocardial biopsies, from patients suffering from cardiac diseases in the Amazon region. Six samples that were collected from three patients were analysed by RT-PCR showing 3 positive and 3 negative results. These preliminary findings suggest the participation of enteroviruses in the etiology of cardiac diseases, mainly myocarditis, and warrant further and broader local studies on this subject.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Enterovirus
/
Enterovirus Infections
/
Heart
/
Heart Diseases
/
Myocardium
Type of study:
Diagnostic study
/
Etiology study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
1998
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Nacional de Saúde/BR
Similar
MEDLINE
...
LILACS
LIS