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Avaliação dos fatores de risco e dos resultados do tratamento percutâneo da estenose da anastomose bilio-entérica em crianças submetidas ao transplante de fígado / Risk factors and results evaluation of percutaneous treatment of bilio-enteric anastomotic structure
São Paulo; s.n; 2007. 127 p. ilus, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-464470
RESUMO
Neste estudo foram avaliados dados de maior relação com a estenose da anastomose bilio-entérica, fatores de risco, tempo de surgimento, tempo de drenagem mais adequado, resposta e complicações do tratamento percutâneo. Trinta e cinco crianças foram avaliadas, retrospectiva e prospectivamente, no período de 1993 a 2006. Das variáveis analisadas, a cirurgia de Kasai associou-se com melhor resposta terapêutica (p = 0,080). Houve adequada resposta nos grupos submetidos a uma ou duas sessões de tratamento. Biópsia hepática com padrão biliar e elevação de gamaglutamiltransferase estiveram mais presentes nos pacientes com estenose. A estenose ocorreu mais freqüentemente após o primeiro ano do transplante de fígado. Pacientes drenados, em média, por dez meses apresentaram melhores resultados. O prolongamento da drenagem associou-se com maiores complicações. O tratamento percutâneo (dilatação e drenagem) é eficaz, seguro e com baixa taxa de complicações.
ABSTRACT
In this study most relevant data related to bilioenteric anastomotic stenosis, their risk factors, time of appearance, the most suitable drainage time, treatment response and complications were evaluated. Thirty five children were studied prospetively and retrospectively between 1993 and 2006. Kasai surgery was associated with best response to the treatment (p=0,08). Best treatment results were observed in the group of patients submitted to one or two sessions of treatment. Hystological findings suggesting biliary obstruction and elevated gamaglutamiltransferase levels were more evident in the group with anastomotic biliary strictures. Strictures were detected more frequently after first year of liver transplantation. Best results were found in patients with ten months mean drainage period. The increase of drainage time is associated with more complications. The percutaneous treatment (dilatation and drainage) is effective, safe and with lower complications rate.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Drainage / Liver Transplantation / Constriction, Pathologic Type of study: Etiology study / Risk factors Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Pregnancy Language: Portuguese Year: 2007 Type: Thesis

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Full text: Available Index: LILACS (Americas) Main subject: Drainage / Liver Transplantation / Constriction, Pathologic Type of study: Etiology study / Risk factors Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Pregnancy Language: Portuguese Year: 2007 Type: Thesis