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Predição da pré-eclâmpsia pelo estudo dopplervelocimétrico endovaginal das artérias uterinas entre 11-13 e 20-24 semanas de gestação / Screening for pre-eclampsia by transvaginal uterine artery Doppler at 11-13 and 20-24 weeks gestation
São Paulo; s.n; 2007. 117 p. ilus, tab, graf.
Thesis in Portuguese | LILACS | ID: lil-464479
RESUMO
Este estudo prospectivo observacional foi realizado na Clínica Obstétrica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, e envolveu 645 gestações únicas submetidas a estudos dopplervelocimétricos endovaginais das artérias uterinas entre 11-13 e 20-24 semanas. Os resultados demonstram que na primeira fase, o exame dopplervelocimétrico não é útil para identificação de gestações com risco aumentado para pré-eclâmpsia. Já entre 20 e 24 semanas, índices dopplervelocimétricos aumentados e presença de incisura bilateral, de forma independente, indicam risco significativamente aumentado. Todavia baixos valores de sensibilidade e valor preditivo positivo não encorajam o uso deste método para predição da pré-eclâmpsia em nossa população.
ABSTRACT
This was a prospective observational study conducted at the Department of Obstetrics, São Paulo University Medical School and involved 645 singleton pregnancies that had uterine artery Doppler examination at 11-13 and 20-24 weeks. Our results showed that during the first trimester, uterine artery Doppler examination is not useful in identifying pregnancies at increased risk of pre-eclampsia. Whereas in the second stage, increased impedance to flow and the presence of bilateral notches were both significantly, and independently associated with increased risk. However due to low sensitivity and positive predictive values, uterine artery Doppler examination is not recommended as an effective screening method for pre-eclampsia in our population.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Pre-Eclampsia / Gestational Age / Ultrasonography, Doppler, Color Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors / Screening study Limits: Female / Humans / Pregnancy Language: Portuguese Year: 2007 Type: Thesis

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Full text: Available Index: LILACS (Americas) Main subject: Pre-Eclampsia / Gestational Age / Ultrasonography, Doppler, Color Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors / Screening study Limits: Female / Humans / Pregnancy Language: Portuguese Year: 2007 Type: Thesis