Syndromes related to sodium and arginine vasopressin alterations in post-operative neurosurgery
Arq. neuropsiquiatr
;
65(3b): 745-751, set. 2007. tab
Article
in English
| LILACS
| ID: lil-465174
ABSTRACT
BACKGROUND:
Cerebral salt wasting syndrome (CSWS), syndrome of inappropriate antidiuretic hormone secretion (SIADH) and diabetes insipidus (DI) are frequently found in postoperative neurosurgery.PURPOSE:
To identify these syndromes following neurosurgery.METHOD:
The study included 30 patients who had been submitted to tumor resection and cerebral aneurysm clipping. Sodium levels in serum and urine and urine volume were measured daily up to the 5th day following surgery. Plasma arginine vasopressin (AVP) was measured on the first, third and fifth days post-surgery.RESULTS:
CSWS was found in 27/30 patients (90 percent), in 14 (46.7 percent) of whom it was associated with a reduction in the levels of plasma AVP (mix syndrome). SIADH was found in 3/30 patients (10 percent). There was no difference between the two groups of patients.CONCLUSION:
CSWS was the most common syndrome found, and in half the cases it was associated with DI. SIADH was the least frequent syndrome found.RESUMO
INTRODUÇÃO:
A síndrome perdedora de sal (SPS), síndrome da secreção inapropriada do hormônio antidiurético (SIADH) e diabetes insipidus (DI) são freqüentemente encontradas no pós-operatório de neurocirurgia.OBJETIVO:
Identificar essas síndromes relacionadas à neurocirurgia.MÉTODO:
Foram estudados 30 pacientes submetidos à ressecção de tumor (n=19) e clipagem de aneurisma (n=11) cerebral durante os primeiros cinco dias do pós-operatório. Os pacientes foram submetidos a dosagens diárias de sódio sérico e urinário até o 5° dia pós-operatório, com controle de volume urinário neste período e dosagem de arginina-vasopressina (AVP) plasmática no 1°, 3° e 5° dias pós-operatórios.RESULTADOS:
A SPS foi encontrada em 27/30 pacientes (90 por cento), em 14/27 (46,7 por cento) associada à diminuição dos níveis de AVP plasmática (síndrome mista). A SIADH foi encontrada em 3/30 pacientes (10 por cento). Não houve diferença entre os dois grupos de pacientes.CONCLUSÃO:
A SPS foi a síndrome mais freqüente, em metade de casos associada ao DI. A SIADH foi a menos freqüente.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Postoperative Complications
/
Sodium
/
Brain Neoplasms
/
Arginine Vasopressin
/
Intracranial Aneurysm
/
Diabetes Insipidus
/
Inappropriate ADH Syndrome
Type of study:
Diagnostic study
/
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
2007
Type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
State University of Campinas/BR
/
University of São Paulo/BR
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