Factores determinantes en la aparición de fibrilación auricular post-cirugía de revascularización miocárdica: un estudio prospectivo / Risk factors for postoperative atrial fibrillation after coronary artery bypass grafting: a prospective analysis
Rev. méd. Chile
;
135(8): 967-974, ago. 2007. graf, tab
Article
in Spanish
| LILACS
| ID: lil-466495
ABSTRACT
Background:
Atrial fibrillation (AF) is a relevant complication after coronary artery bypass grafting (CABG). However there is controversy regarding possible contributing factors.Aim:
To study the incidence of AF, its risk factors and its repercussion on hospital stay and charges, in patients undergoing CABG. Material andmethods:
We prospectively collected information from all patients undergoing CABG in our institution, including demographic, surgical and laboratory variables. Exclusion criteria were chronic AF, recent onset AF and patients who needed additional surgical procedures. The primary endpoint was the incidence of AF during the hospital stay. Secondary endpoints were hospital length of stay and hospital charges.Results:
We included 250 patients aged 62±9 years (199 males) in the analysis. Incidence of AF was 22 percent (54 patients). Multivariable analysis showed that age (Odds Ratio (OR) =1.10), previous CABG (OR =9.39), previous use of ACE inhibitors (OR =3.28) and aortic clamp >57 minutes (OR =3.97) were significantly associated with an increased risk of postoperative AF. Previous use of beta-blockers was associated with risk reduction (OR =0.43). Patients who developed AF had a longer hospital stay (p <0.001) and higher hospital charges (p =0.003).Conclusion:
AF is a frequent complication in patients undergoing CABG. Risk factors are age, time of aortic clamp, previous CABG and ACE inhibitors. Beta-blockers may prevent its occurrence. Furthermore, AF has a negative impact on both hospital stay and hospital charges.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Atrial Fibrillation
/
Coronary Artery Bypass
/
Coronary Disease
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2007
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
Similar
MEDLINE
...
LILACS
LIS