In vitro susceptibility testing of dermatophytes isolated from pediatric cases in Nigeria against five antifungals
Rev. Inst. Med. Trop. Säo Paulo
;
49(5): 293-295, Sept.-Oct. 2007. tab
Article
in English
| LILACS
| ID: lil-467368
ABSTRACT
The antifungal activities of itraconazole, ketoconazole, fluconazole, terbinafine and griseofulvin were tested by broth microdilution methods against 71 isolates of dermatophytes isolated from Nigerian children. Most drugs were very active against all the dermatophytes and the MIC 90 ranged from 0.03 to 8.0 µg/mL. This appears to be the first documented data on the antifungal susceptibility testing of isolates of dermatophytes from Nigerian children.
RESUMO
Atividades antifúngicas de itraconazole, ketoconazole, fluconazole, terbinafine e griseofulvina foram testadas por métodos de microdiluição em caldo contra 71 isolados de dermatófitos de crianças nigerianas. A maioria das drogas foi muito ativa contra todos os dermatófitos e o MIC 90 variou de 0,03 a 8,0 µg/mL. Estes parecem ser os primeiros dados documentados sobre os testes de susceptibilidade antifúngica de isolados de dermatófitos de crianças nigerianas.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Arthrodermataceae
/
Antifungal Agents
Limits:
Child
/
Humans
Country/Region as subject:
Africa
Language:
English
Journal:
Rev. Inst. Med. Trop. Säo Paulo
Journal subject:
Tropical Medicine
Year:
2007
Type:
Article
Affiliation country:
Nigeria
Institution/Affiliation country:
Ebonyi State University/NG
/
University of Nigeria/NG
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