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Estudio de enfermedad celíaca en pacientes con psoriasis / Frequency of celiac disease among patients with psoriasis
Calderón H., Perla; Valdés A., Pilar; Zemelman D., Viviana; Poniachik T., Jaime; Hurtado H., Carmen; Garmendia M., María Luisa; Abumohor G., Patricia; Echavarri P., María Cristina.
  • Calderón H., Perla; Universidad de Chile. Hospital Clínico. Servicio de Dermatología. CL
  • Valdés A., Pilar; Universidad de Chile. Hospital Clínico. Servicio de Dermatología. CL
  • Zemelman D., Viviana; Universidad de Chile. Hospital Clínico. Servicio de Dermatología. CL
  • Poniachik T., Jaime; Universidad de Chile. Hospital Clínico. Servicio de Gastroenterología. CL
  • Hurtado H., Carmen; Universidad de Chile. Hospital Clínico. Servicio de Gastroenterología. CL
  • Garmendia M., María Luisa; Universidad de Chile. Facultad de Medicina. Escuela de Salud Pública. CL
  • Abumohor G., Patricia; Universidad de Chile. Hospital Clínico. Servicio de Inmunología. CL
  • Echavarri P., María Cristina; Universidad de Chile. Hospital Clínico. Servicio de Inmunología. CL
Rev. méd. Chile ; 135(10): 1296-1303, oct. 2007. tab
Article in Spanish | LILACS | ID: lil-470702
ABSTRACT

Background:

A possible relationship has been reported between psoriasis and celiac disease, with common pathogenic mechanisms that may need further investigation.

Aim:

To investigate the presence of clinical and serological markers for celiac disease in a group of Chilean psoriatic patients. Material and

methods:

We included 80 psoriatic patients (42 males) aged 16 to 79 years, whose serum was tested for antitransglutaminase antibodies (ATGA) and antiendomysial antibodies (AEMA). Patients with weakly positive AEMA tests were also tested for antigliadin antibodies (AGA).

Results:

In six patients (7.5 percent), AEMA and AGA were positive and one patient was positive for ATGA. An upper gastrointestinal endoscopy and duodenal biopsy was offered to these six patients and five accepted the procedure. Only one had a pathological diagnosis of celiac disease.

Conclusions:

Only one of 80 patients with psoriasis had celiac disease (1.2 percent). Other four patients with positive serologic markers had a normal duodenal biopsy. This group of patients may have latent celiac disease and they should be followed up.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Psoriasis / Autoantibodies / Celiac Disease / Transglutaminases / Gliadin Type of study: Diagnostic study / Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2007 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL

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Full text: Available Index: LILACS (Americas) Main subject: Psoriasis / Autoantibodies / Celiac Disease / Transglutaminases / Gliadin Type of study: Diagnostic study / Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2007 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL