Aminotransferasas séricas en pacientes con Dengue tipo 3 / Aminotransferases serum levels in patients with Dengue type 3
Rev. méd. Chile
;
135(10): 1304-1312, oct. 2007. graf, tab
Article
in Spanish
| LILACS
| ID: lil-470710
ABSTRACT
Background:
Dengue infections may affect the liver, causing inflammation and compromising its function.Aim:
To determine serum aminotransferases in patients with Dengue. Material andmethods:
One hundred eighty four patients with Dengue confirmed with anti-Dengue IgG and IgM antibodies measured by ELISA, aged 1 month to 79 years, were studied. As controls, 40 patients with acute hepatitis B virus infection aged 11 to 59 years and 40 healthy individuals, aged 14 to 55 years, were also studied. Alanine and aspartate aminotransferases (ALT and AST) were determined using a colorimetric method.Results:
Sixty one percent of patients with Dengue had elevated aminotransferase levels. In patients with Dengue and hepatitis B, mean ALT levels were 21.3±8.4 and 29.7±18.8 U/I, respectively. Mean AST values were 37.3±19, 19.6± 16.4 and 4.3±1.7 U/I in patients with Dengue, hepatitis B and controls, respectively. During the year 2001, there was an increase in the number of cases with hemorrhagic fever caused by Dengue and 65 percent had elevation of aminotransferases.Conclusions:
An increase in aminotransf erase levels is common in patients with Dengue.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Aspartate Aminotransferases
/
Dengue
/
Dengue Virus
/
Alanine Transaminase
/
Hepatitis B
Type of study:
Observational study
Limits:
Adolescent
/
Adult
/
Aged
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2007
Type:
Article
/
Project document
Affiliation country:
Venezuela
Institution/Affiliation country:
Universidad del Zulia/VE
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