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Aminotransferasas séricas en pacientes con Dengue tipo 3 / Aminotransferases serum levels in patients with Dengue type 3
Valero C., Nereida; Reyes V., Ivette; Larreal E., Yraima; Maldonado E., Mery.
  • Valero C., Nereida; Universidad del Zulia. Instituto de Investigaciones Clínicas Dr. Américo Negrette. Maracaibo. VE
  • Reyes V., Ivette; Universidad del Zulia. Instituto de Investigaciones Clínicas Dr. Américo Negrette. Maracaibo. VE
  • Larreal E., Yraima; Universidad del Zulia. Instituto de Investigaciones Clínicas Dr. Américo Negrette. Maracaibo. VE
  • Maldonado E., Mery; Universidad del Zulia. Instituto de Investigaciones Clínicas Dr. Américo Negrette. Maracaibo. VE
Rev. méd. Chile ; 135(10): 1304-1312, oct. 2007. graf, tab
Article in Spanish | LILACS | ID: lil-470710
ABSTRACT

Background:

Dengue infections may affect the liver, causing inflammation and compromising its function.

Aim:

To determine serum aminotransferases in patients with Dengue. Material and

methods:

One hundred eighty four patients with Dengue confirmed with anti-Dengue IgG and IgM antibodies measured by ELISA, aged 1 month to 79 years, were studied. As controls, 40 patients with acute hepatitis B virus infection aged 11 to 59 years and 40 healthy individuals, aged 14 to 55 years, were also studied. Alanine and aspartate aminotransferases (ALT and AST) were determined using a colorimetric method.

Results:

Sixty one percent of patients with Dengue had elevated aminotransferase levels. In patients with Dengue and hepatitis B, mean ALT levels were 21.3±8.4 and 29.7±18.8 U/I, respectively. Mean AST values were 37.3±19, 19.6± 16.4 and 4.3±1.7 U/I in patients with Dengue, hepatitis B and controls, respectively. During the year 2001, there was an increase in the number of cases with hemorrhagic fever caused by Dengue and 65 percent had elevation of aminotransferases.

Conclusions:

An increase in aminotransf erase levels is common in patients with Dengue.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Aspartate Aminotransferases / Dengue / Dengue Virus / Alanine Transaminase / Hepatitis B Type of study: Observational study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2007 Type: Article / Project document Affiliation country: Venezuela Institution/Affiliation country: Universidad del Zulia/VE

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Full text: Available Index: LILACS (Americas) Main subject: Aspartate Aminotransferases / Dengue / Dengue Virus / Alanine Transaminase / Hepatitis B Type of study: Observational study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Infant, Newborn Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2007 Type: Article / Project document Affiliation country: Venezuela Institution/Affiliation country: Universidad del Zulia/VE