Coristoma pancreático en la vesícula biliar: Reporte de dos casos / Pancreatic choristoma in the gallbladder: Report of two cases
Rev. méd. Chile
;
135(10): 1318-1322, oct. 2007. ilus
Article
in Spanish
| LILACS
| ID: lil-470712
ABSTRACT
Pancreatic choristoma is the ocurrence of normal pancreatic tissue in an abnormal location without any anatomic continuity with the main body of the gland. Although heterotopia is uncommon in the gallbladder and biliary tract, anecdotic cases of gastric mucosa, liver, adrenal gland and pancreas among other tissues have been described. We report an eight year-old male and a 22 year-old female, electively operated for symptomatic cholelithiasis. On pathology, a nodule identified as a pancreatic endocrine and exocrine choristoma, was found in the gallbladder wall of both patients. We employed immunohistochemistry to characterize this choristoma. Tubular and epithelial structures were immunoreactive to cytokeratins 7, 8, 18, 19 and 20 and to CA19-9. Exocrine activity was documented by immunoreactivity to al-antitrypsin and al-chemotrypsin. Other immunohistochemical markers such as insulin and somatostatin were positive identifying endocrine activity.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pancreas
/
Choristoma
/
Gallbladder Diseases
Type of study:
Prognostic study
Limits:
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2007
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Histomed/CL
/
Hospital de La Serena/CL
/
Hospital de Ovalle/CL
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