First encounter of subclinical human Leishmania (Viannia) infection in State of Rio Grande do Sul, Brazil
Mem. Inst. Oswaldo Cruz
;
102(8): 1003-1005, Dec. 2007.
Article
in English
| LILACS
| ID: lil-471858
ABSTRACT
The objective of the present study was to evaluate the specificity of the Montenegro skin test (MST) in an area in Brazil, state of Grande do Sul State (RS), which was considered to be non-endemic for leishmaniasis. Sixty subjects presented a positive MST and were reevaluated by clinical examination, serology and polymerase chain reaction (PCR) of peripheral blood for the detection of subclinical Leishmania infection. None of the subjects presented clinical signs or symptoms of current leishmaniasis or a history of the disease.Leishmania (Viannia) DNA was detected in blood by PCR and hybridization in one subject. The PCR skin test-positive individual remained asymptomatic throughout the study. Clinical examination showed no scars suggestive of past cutaneous leishmaniasis. Human subclinical infection with Leishmania (Viannia) in RS was confirmed by PCR. This is the first report of subclinical infection with this parasite in the human population of this area.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Leishmania braziliensis
/
Leishmaniasis, Cutaneous
Type of study:
Diagnostic study
/
Observational study
Limits:
Animals
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
National Reference Center for Diagnosis of Tegumentary Leishmaniasis/BR
/
Universidade Federal do Rio de Janeiro/BR
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