Antigenic and genomic characterization of adenovirus associated to respiratory infections in children living in Northeast Brazil
Mem. Inst. Oswaldo Cruz
;
102(8): 937-941, Dec. 2007. ilus
Article
in English
| LILACS
| ID: lil-471860
ABSTRACT
From January to December 1998, nasopharyngeal aspirates were obtained from 482 children with acute respiratory infections attended in emergence department and wards of a teaching hospital in the city of Salvador, Brazil. The samples were tested for the presence of adenovirus by isolation in tissue culture and indirect immunofluorescence assay. Eleven adenoviruses were detected by both methods in the same clinical samples. Infections by adenovirus were observed during seven months of the year without association with rainy season. Genome analysis was performed on these 11 isolates. Species C was represented by serotypes 1, 2 and 5. Within species B, only serotype 7 (Ad7) was detected. Two genomic variants of Ad1, two variants of Ad2, one of Ad5, and one of Ad7 (7h) were identified. This is the first study of molecular epidemiology of adenovirus associated to acute respiratory infections in children living in Northeast Brazil, and contributes to a better understanding of adenovirus infections in the country.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Respiratory Tract Infections
/
Adenovirus Infections, Human
/
Adenoviruses, Human
Type of study:
Risk factors
Limits:
Child
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2007
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Fiocruz/BR
/
Universidade Federal do Ceará/BR
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