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Skin test reactivity to aeroallergens in Jamaicans: relationship to asthma / Reactividad de la prueba cutánea frente a aeroalérgenos en los jamaicanos: relación con el asma
Knight-Madden, J; Forrester, T. E; Hambleton, I. R; Lewis, N; Greenough, A.
  • Knight-Madden, J; The University of the West Indies. Tropical Medicine Research Institute. Sickle Cell Unit. JM
  • Forrester, T. E; s.af
  • Hambleton, I. R; s.af
  • Lewis, N; s.af
  • Greenough, A; s.af
West Indian med. j ; 55(3): 142-147, Jun. 2006.
Article in English | LILACS | ID: lil-472330
ABSTRACT

BACKGROUND:

Asthma causes significant morbidity and mortality in the developing world. It is thus important to identify modifiable risk factors.

OBJECTIVES:

To undertake a cross-sectional study to determine the prevalence of skin test reactivity to aeroallergens in Jamaican children and adults and the relationship of the diagnosis of asthma to the pattern of skin test positivity.

METHODS:

One hundred and sixty subjects without the sickle cell gene (genotype AA), eighty adults and eighty children, were recruited. Skin testing to seven aeroallergens was undertaken (atopy being diagnosed if there were at least one positive reaction). Asthma status was determined by a questionnaire and/or medical records.

RESULTS:

Twenty-seven (34) of the children and forty-one (51) of the adults were skin test positive to at least one aeroallergen. The most common positive responses in both age groups were to Dermatophagoides farinae, Dermatophagoides pteronyssinus and cockroach mix-(German and American). All adult asthmatics with current symptoms reacted to cockroach allergen.

CONCLUSIONS:

Appropriate steps to reduce cockroaches and cockroach sensitization might positively impact on asthma morbidity in Jamaica.
RESUMEN
ANTECíENTES El asma causa morbilidad y mortalidad significativas en el mundo en desarrollo. Por lo tanto, es importante identificar los factores de riesgo modificables.

OBJETIVOS:

Llevar a cabo un estudio transversal a fin de determinar la prevalencia de la reactividad de la prueba cutánea frente a los aeroalérgenos en niños y adultos jamaicanos, y la relación del diagnóstico del asma con el patrón de positividad de la prueba cutánea.

MÉTODOS:

Se reclutaron ciento sesenta sujetos AA (sin genes falciformes), ochenta adultos y ochenta niños. Se llevaron a cabo pruebas cutáneas frente a siete aeroalérgenos (diagnosticándose atopia si se producía al menos una reacción positiva). El estatus asmático se determinó mediante encuestas y/o historias clínicas.

RESULTADOS:

Veintisiete (34%) de los niños y cuarenta y uno (51%) de los adultos, resultaron positivos en la prueba cutánea, al menos a un aeroalérgeno. Las respuestas positivas más comunes en ambos grupos de edad fueron frente a Dermatophagoides farinae, Dermatophagoides pteronyssinus, y mezcla de cucarachas (alemanas y americanas). Todos los asmáticos adultos con síntomas usuales reaccionaron al alérgeno de la cucaracha.

CONCLUSIONES:

Medidas apropiadas a fin de reducir las cucarachas y la sensibilización a las cucarachas podría tener un impacto positivo en la morbilidad por asma en Jamaica.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Asthma / Skin Tests / Allergens / Hypersensitivity, Immediate Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Child / Female / Humans / Male Country/Region as subject: English Caribbean / Jamaica Language: English Journal: West Indian med. j Journal subject: Medicine Year: 2006 Type: Article Affiliation country: Jamaica Institution/Affiliation country: The University of the West Indies/JM

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Full text: Available Index: LILACS (Americas) Main subject: Asthma / Skin Tests / Allergens / Hypersensitivity, Immediate Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Child / Female / Humans / Male Country/Region as subject: English Caribbean / Jamaica Language: English Journal: West Indian med. j Journal subject: Medicine Year: 2006 Type: Article Affiliation country: Jamaica Institution/Affiliation country: The University of the West Indies/JM