Successful treatment of disseminated Aspergillosis in a leukemic child
P. R. health sci. j
;
24(2): 157-160, Jun. 2005.
Article
in English
| LILACS
| ID: lil-472965
ABSTRACT
The incidence of severe fungal infections in the immunocompromised patient with malignancies has increased in recent years. This appears to be associated to the profound periods of immunosuppression and the extended use of broad spectrum antibiotics. Aspergillosis is the second most common fungal infection reported in the immunocompromised cancer patients. In patients with advanced immunosupression, the mortality due to invasive aspergillosis approaches 100despite treatment with antifungal agents. Reports of complete or partial response to echinocandins are well demonstrated in adults, but very limited in the pediatric population. This report describes the case of a child with relapsed acute lymphoblastic leukemia (ALL) who developed cutaneous aspergillosis and subsequent multiorgan dissemination during therapeutic induction and was treated successfuly with caspofungin acetate.
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Index:
LILACS (Americas)
Main subject:
Aspergillosis
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Type of study:
Diagnostic study
Limits:
Child
/
Female
/
Humans
Language:
English
Journal:
P. R. health sci. j
Journal subject:
Medicine
Year:
2005
Type:
Article
Affiliation country:
Puerto Rico
Institution/Affiliation country:
University of Puerto Rico/PR
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