Sentinel node in breast cancer: experience with periareolar 99mTc-Dextran / Ganglio centinela en cancer de mama: experiencia con 99mTc-Dextran periareolar
Rev. med. nucl. Alasbimn j
;
9(37)July 2007. tab
Article
in English, Spanish
| LILACS
| ID: lil-474909
RESUMEN
Se presentan los resultados de la biopsia de ganglio centinela en 77 mujeres portadoras de cáncer ductal in situ (CDIS) multifocal o cáncer de mama T1-2 , todas con axila clínicamente negativa, utilizando inyección periareolar intradérmica de 99mTc-Dextran, linfocintigrafía y detección radioisotópica intraoperatoria. En 72/77 pacientes además se usó colorante azul de Isosulfan. Se obtuvo al menos un ganglio centinela en la totalidad de las pacientes. Se encontró 1 o 2 ganglios metastásicos en 14 pacientes. En 13 de ellas el ganglio centinela estaba comprometido y en 6/10 con disección axilar (DA) el resto de los ganglios estaban negativos.
ABSTRACT
Sentinel lymph node biopsy (SLNB) was performed in 77 consecutive women with clinically node-negative T1 and T2 breast cancer or multifocal ductal carcinoma in situ (DCIS). They had periareolar subdermal injection of 99mTc-Dextran, preoperative lymphoscintigraphy and intraoperative handheld probe detection. Isosulfan blue dye was also used in 72/77 patients. At least one sentinel node was found at surgery for all patients. In 14 patients one or two metastatic nodes were found, 13 of them in the sentinel node(s). Axillary lymph node dissection was otherwise negative in 6/10 positive SLNB patients.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Breast Neoplasms
/
Organotechnetium Compounds
/
Carcinoma, Intraductal, Noninfiltrating
/
Sentinel Lymph Node Biopsy
/
Lymph Nodes
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
/
Spanish
Journal:
Rev. med. nucl. Alasbimn j
Journal subject:
Nuclear Medicine
Year:
2007
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Clínica Las Condes/CL
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