Total agenesis of the corpus callosum in a patient with childhood-onset schizophrenia
Arq. neuropsiquiatr
;
65(4b): 1216-1219, dez. 2007. ilus
Article
in English
| LILACS
| ID: lil-477774
ABSTRACT
The hypothesis that schizophrenia involves aberrant inter-hemispheric communication has a long pedigree, however its precise role remains unclear. We therefore report the case of a total agenesis of the corpus callosum in a 21-year-old man with childhood-onset schizophrenia. The presence of schizophrenia with very early onset on absence of corpus callosum offers an opportunity to examine neurodevelopmental model and theories regarding to interhemispheric communication in the pathogenesis of psychosis.
RESUMO
A hipótese que a esquizofrenia envolve comunicação inter-hemisférica aberrante possui longa tradição, entretanto seu papel permanece incerto. Nós relatamos um caso de agenesia total do corpo caloso em um homem de 21 anos portador de esquizofrenia de início na infância. A associação de esquizofrenia de início precoce na ausência de corpo caloso oferece uma oportunidade para exame do modelo neurodesenvolvimental e de teorias que envolvem a comunicação interemisférica na patogênese da psicose.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Schizophrenia, Childhood
/
Corpus Callosum
Type of study:
Prognostic study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Arq. neuropsiquiatr
Journal subject:
Neurology
/
Psychiatry
Year:
2007
Type:
Article
Affiliation country:
Brazil
/
United kingdom
Institution/Affiliation country:
Institute of Psychiatry/GB
/
University of Manchester/GB
/
University of São Paulo/BR
Similar
MEDLINE
...
LILACS
LIS