Policondritis recurrente. Estudio de 19 casos en Colombia / Relapsing polychondritis. An study of 19 cases in Colombia

ABSTRACT

Objective: To describe clinical and paraclinical involvement in RP in a Colombian populationand compare it with another series previously published.Methods and materials Retrospective review of 19 cases of RP presented in 4 rheumatologycenters in our country in the last 10 years. All patients met diagnostic criteria previouslyestablished. In every case, each clinical feature was analized and then compared with another9 series of RP previously published between 1966 y 2007.Results: Mean age at diagnosis was 46 years. A female predominance was observed ina relation 41. Mean follow-up was 4 years. Auricular condritis was the initial clinicalfeature in 89 percent of patients and finally was observed in the 100 percent of our report. Comparedwith other series, we found less frequently arthritis (21percent), ocular (10percent) and dermatologicinvolvement (10percent). Renal and neurologic involvement and the association between RPand another autoimmune disorder were found in the expected frequency. We not observedany cardiovascular involvement in our serie. All of the patients received corticosteroidsand 57percent had had another immunosuppressive medication. Observed mortality was 10percentby complications associated to RP.Conclusions: In contrast with another series from Caucasian and Oriental population, weobserved a marked predominance of female sex, a minor frequency of systemic involvementand auricular condritis is our most frequent initial clinical feature. Probably, these findingsare the result of a different genetic, immunological and environmental background.

RESUMEN

Objetivo: Describir el comportamiento clínico y paraclínico de la PR en la poblacióncolombiana y comparar nuestros resultados con otras series publicadas.Materiales y métodos: Estudio descriptivo observacional de 19 casos de PR presentadosen 4 centros de reumatología del país durante los últimos 10 años. Los pacientes cumplieroncon el diagnóstico de PR de acuerdo al parámetro establecido...