Púrpura trombocitopénico trombótico con respuesta exitosa a vincristina / Successful treatment of thrombotic thrombocytopenic purpura with vincristine report of one case
Rev. méd. Chile
;
135(12): 1572-1576, dic. 2007. graf, tab
Article
in Spanish
| LILACS
| ID: lil-477988
ABSTRACT
Thrombotic thrombocytopenic purpura presents as a multisystemic disease with thrombocytopenia, microangiopathic hemolytic anemia, fever, neurological and renal involvement. We report a 24 years-old male presenting with purpura and a generalized seizure. His blood tests showed an hemolytic anemia, unconjungated hyperbilirubinemia, increased lactated dehydrogenase, thrombocytopenia and impairment of renal function. He was initially treated with daily plasmapheresis and steroids without improvement. Due to persistence of the disease, he was treated with two doses of intravenous vincristine in four days, with clinical and laboratory improvement. He was discharged 40 days after the last dose of vincristine, in good conditions.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Purpura, Thrombotic Thrombocytopenic
/
Vincristine
/
Fibrinolytic Agents
Type of study:
Diagnostic study
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2007
Type:
Article
Affiliation country:
Chile
/
Colombia
Institution/Affiliation country:
Hospital Parroquial de San Bernardo/CL
/
Universidad de Los Andes/CO
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