Adenoviruses C in non-hospitalized Mexican children older than five years of age with acute respiratory infection
Mem. Inst. Oswaldo Cruz
;
103(2): 195-200, Mar. 2008. graf, tab
Article
in English
| LILACS
| ID: lil-480634
ABSTRACT
Adenoviruses (AdV) are commonly involved in acute respiratory infections (ARI), which cause high morbidity and mortality in children. AdV are grouped in six species (A-F), which are associated with a wide range of diseases. The aim of this study was to identify the AdV species infecting non-hospitalized Mexican children with ARI symptoms, attending to the same school. For that, a PCR/RFLP assay was designed for a region of the hexon gene, which was chosen, based on the bioinformatical analysis of AdV genomes obtained from GenBank. A total of 100 children's nasopharyngeal samples were collected from January to June, 2005, and used for viral isolation in A549 cells and PCR/RFLP analysis. Only 15 samples produced cytopathic effect, and in all of them AdV C was identified. AdV C was also identified in eight additional nasopharyngeal samples which were negative for viral isolation. In summary, this outpatient population showed a rate of AdV infection of 23 percent, and only AdV C was detected.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Respiratory Tract Infections
/
Adenovirus Infections, Human
/
Adenoviruses, Human
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Child
/
Female
/
Humans
/
Male
Country/Region as subject:
Mexico
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2008
Type:
Article
/
Project document
Affiliation country:
Mexico
Institution/Affiliation country:
Instituto Nacional de Enfermedades Respiratorias/MX
/
Instituto Politécnico Naciona/MX
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