Is brain banking of psychiatric cases valuable for neurobiological research?: [review]
Clinics
;
63(2): 255-266, 2008. ilus, tab
Article
in English
| LILACS
| ID: lil-481056
ABSTRACT
It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Schizophrenia
/
Tissue Banks
/
Bipolar Disorder
/
Brain
Limits:
Humans
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2008
Type:
Article
Affiliation country:
Germany
Institution/Affiliation country:
University of Goettingen/DE
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