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Is brain banking of psychiatric cases valuable for neurobiological research?: [review]
Schmitt, Andrea; Parlapani, Eleni; Bauer, Manfred; Heinsen, Helmut; Falkai, Peter.
  • Schmitt, Andrea; University of Goettingen. Department of Psychiatry. Goettingen. DE
  • Parlapani, Eleni; University of Goettingen. Department of Psychiatry. Goettingen. DE
  • Bauer, Manfred; University of Goettingen. Department of Psychiatry. Goettingen. DE
  • Heinsen, Helmut; University of Goettingen. Department of Psychiatry. Goettingen. DE
  • Falkai, Peter; University of Goettingen. Department of Psychiatry. Goettingen. DE
Clinics ; 63(2): 255-266, 2008. ilus, tab
Article in English | LILACS | ID: lil-481056
ABSTRACT
It is widely accepted that neurobiological abnormalities underlie the symptoms of psychiatric disorders such as schizophrenia and unipolar or bipolar affective disorders. New molecular methods, computer-assisted quantification techniques and neurobiological investigation methods that can be applied to the human brain are all used in post-mortem investigations of psychiatric disorders. The following article describes modern quantitative methods and recent post-mortem findings in schizophrenia and affective disorders. Using our brain bank as an example, necessary considerations of modern brain banking are addressed such as ethical considerations, clinical work-up, preparation techniques and the organization of a brain bank, the value of modern brain banking for investigations of psychiatric disorders is summarized.
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Full text: Available Index: LILACS (Americas) Main subject: Schizophrenia / Tissue Banks / Bipolar Disorder / Brain Limits: Humans Language: English Journal: Clinics Journal subject: Medicine Year: 2008 Type: Article Affiliation country: Germany Institution/Affiliation country: University of Goettingen/DE

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Full text: Available Index: LILACS (Americas) Main subject: Schizophrenia / Tissue Banks / Bipolar Disorder / Brain Limits: Humans Language: English Journal: Clinics Journal subject: Medicine Year: 2008 Type: Article Affiliation country: Germany Institution/Affiliation country: University of Goettingen/DE