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Development of Candida-associated denture stomatitis: new insights: [review]
Pereira-Cenci, Tatiana; Del Bel Cury, Altair Antoninha; Crielaard, Wim; Ten Cate, Jacob Martien.
  • Pereira-Cenci, Tatiana; University of Campinas. Dental School of Piracicaba. Department of Prosthodontics and Periodontology. Campinas. BR
  • Del Bel Cury, Altair Antoninha; University of Campinas. Dental School of Piracicaba. Department of Prosthodontics and Periodontology. Campinas. BR
  • Crielaard, Wim; Academic Centre for Dentistry Amsterdam. Department of Cariology, Endodontology Pedodontology. Amsterdam. NL
  • Ten Cate, Jacob Martien; Academic Centre for Dentistry Amsterdam. Department of Cariology, Endodontology Pedodontology. Amsterdam. NL
J. appl. oral sci ; 16(2): 86-94, Mar.-Apr. 2008. ilus
Article in English | LILACS | ID: lil-481303
ABSTRACT
Despite therapeutic progress, opportunistic oral fungal infectious diseases have increased in prevalence, especially in denture wearers. The combination of entrapment of yeast cells in irregularities in denture-base and denture-relining materials, poor oral hygiene and several systemic factors is the most probable cause for the onset of this infectious disease. Hence colonization and growth on prostheses by Candida species are of clinical importance. The purpose of this review is to critically discuss several key factors controlling the adhesion of Candida species which are relevant to denture-associated stomatitis. Although there is some consensus on the role of surface properties, studies on several other factors, as the use of denture liners, salivary properties and yeast-bacterial interactions, have shown contradictory findings. A comprehensive fundamental understanding is hampered by conflicting findings due to the large variations in experimental protocols, while other factors have never been thoroughly studied. Surface free energy and surface roughness control the initial adherence, but temporal changes have not been reported. Neither have in vivo studies shown if the substratum type is critical in dictating biofilm accumulation during longer periods in the oral environment. The contribution of saliva is unclear due to factors like variations in its collection and handling. Initial findings have disclosed that also bacteria are crucial for the successful establishment of Candida in biofilms, but the clinical significance of this observation is yet to be confirmed. In conclusion, there is a need to standardize experimental procedures, to bridge the gap between laboratory and in vivo methodologies and findings and - in general - to thoroughly investigate the factors that modulate the initial attachment and subsequent colonization of denture-base materials and the oral mucosa of patients subjected to Candida infections. Information...
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Full text: Available Index: LILACS (Americas) Main subject: Stomatitis, Denture / Candidiasis, Oral / Dentures Type of study: Practice guideline / Risk factors Limits: Humans Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2008 Type: Article Affiliation country: Brazil / Netherlands Institution/Affiliation country: Academic Centre for Dentistry Amsterdam/NL / University of Campinas/BR

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Full text: Available Index: LILACS (Americas) Main subject: Stomatitis, Denture / Candidiasis, Oral / Dentures Type of study: Practice guideline / Risk factors Limits: Humans Language: English Journal: J. appl. oral sci Journal subject: Dentistry Year: 2008 Type: Article Affiliation country: Brazil / Netherlands Institution/Affiliation country: Academic Centre for Dentistry Amsterdam/NL / University of Campinas/BR