Espessura corneana central e densidade das células endoteliais corneanas centrais após trabeculectomia com e sem mitomicina C / Central corneal thickness and central corneal endothelial cells density after trabeculectomy with and without mitomycin C
Rev. bras. oftalmol
;
67(1): 25-31, jan.-fev. 2008. tab
Article
in Portuguese
| LILACS
| ID: lil-482459
RESUMO
OBJETIVO:
Comparar a espessura corneana central (ECC), a densidade (DCEC) e a área média (ACM) das células endoteliais corneanas centrais após trabeculectomia (TREC) com e sem mitomicina C (MMC).MÉTODOS:
Estudo prospectivo. Foram avaliados 29 olhos divididos em dois grupos TREC com e sem MMC. Realizaram-se os seguintes exames pré-operatoriamente e três e seis meses após a TREC paquimetria ultra-sônica e microscopia especular de não-contato.RESULTADOS:
As variações da ECC, DCEC e ACM dos olhos submetidos a TREC com MMC foram, respectivamente - 11,9±25,7 µm, -169,5±145,3 células/mm² e 42,5±33,4 µm² (três meses); - 7,5±28,1 µm, - 220,6±200,2 células/mm² e 31,5±65,3 µm² (seis meses). As variações da ECC, DCEC e ACM dos olhos submetidos a TREC sem MMC foram, respectivamente - 13,9±16,7 µm, 200,8±155,4 células/mm² e 34,6±52,4 µm² (três meses); - 10,2±15,6 µm, - 277,6±195,7 células/mm² e 34,3±41,0 µm² (seis meses).CONCLUSÃO:
TREC realizada com MMC, quando comparada a TREC sem MMC, não acarretou maior redução da DCEC central.Também não houve variação na ECC e na ACM nos dois grupos, após seis meses de seguimento.ABSTRACT
PURPOSE:
To assess comparatively the central corneal thickness (CCT), the central corneal endothelial cells density (CECD) and mean area (CECAA), of patients who underwent trabeculectomy (Trab) with or without mytomicyn C (MMC).METHODS:
Prospective study. Twenty-nine eyes were divided in two groups Trab with or without MMC. Ultrasonic pachymetry and non-contact specular microscopy were performed pre-operatively and three and six months after Trab. The mean value of the CECD and the low value of the CCT were used.RESULTS:
In the group of Trab with MMC, the variations of the CCT, CECD and CECAA values were, respectively - 11.9±25.7 µm, - 169.5±145.3 cells/mm² and 42.5±33.4 µm² (three months); - 7.5±28.1 µm, - 220.6±200.2 cells/mm² and 31.5±65.3 µm² (six months). In the group of Trab without MMC, the variations of the CCT, CECD and CECAA values were, respectively - 13.9±16.7 µm, - 200.8±155.4 cells/mm² and 34.6±52.4 µm² (three months); - 10.2±15.6 µm, - 277.6±195.7 cells/mm² and 34.3±41.0 µm² (six months).CONCLUSION:
After six months of follow-up, there was no difference in the variations of CCT, CECD and CECAA when Trab with MMC was compared with Trab without MMC.
Full text:
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Index:
LILACS (Americas)
Main subject:
Endothelium, Corneal
/
Trabeculectomy
/
Cell Count
/
Glaucoma
/
Mitomycin
/
Endothelial Cells
/
Microscopy
Type of study:
Observational study
Limits:
Female
/
Humans
/
Male
Language:
Portuguese
Journal:
Rev. bras. oftalmol
Journal subject:
Ophthalmology
Year:
2008
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Minas Gerais/BR
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