Leucoencefalopatía reversible posterior: cuatro casos clínicos / Reversible posterior leukoencephalopathy syndrome in patients with immunosupressive treatment: Report of four cases
Rev. méd. Chile
;
136(1): 93-98, ene. 2008. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-483225
ABSTRACT
Reversible posterior leukoencephalopathy syndrome (PLS) is characterized by headache, clouding of sensorium, visual disturbances and seizures. It is associated to hypertension, renal disease or immunosuppressive therapy. We report three males, aged 9, 12 and 16 years and one female, aged 5 years wih PLS associated to immunosuppressive therapy. All had seizures and three had headache and clouding of sensorium. One case was associated to an hypertensive emergency, one to liver failure and one to high tacrolimus levels. Magnetic resonance imaging showed lesions in the white matter in two patients and in the gray matter in the other two. The lapse between the start of immunosuppressive treatment and neurological symptoms ranged from 4 days to 6 months. All received antiepileptic drugs and immunosuppresive therapy was changed or decreased, with complete clinical recovery.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tacrolimus
/
Posterior Leukoencephalopathy Syndrome
/
Immunosuppressive Agents
/
Anticonvulsants
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2008
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Pontificia Universidad Católica de Chile/CL
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