Caracterização de amostras do vírus da raiva, isoladas nas regiões Norte e Centro-Oeste do Brasil, com anticorpos monoclonais antilissavírus / Antigenic characterization of Brazilian rabies virus isolate North and Central West regions of Brazil with anti-lyssavirus monoclonal antibodies
Arq. bras. med. vet. zootec
;
60(1): 260-262, fev. 2008. tab
Article
in Portuguese
| LILACS
| ID: lil-483285
ABSTRACT
The occurrence of rabies virus antigenic variants in North and Central West regions of Brazil was studied using 61 rabies viruses isolated from different species 30 from domestic dogs, 20 from cattle, four from horses, two from cats, one from a human and four from unidentified species. The isolates were submitted to antigenic analyses by indirect immunofluorescence with a panel of 12 monoclonal antibodies (Mabs) to lyssavirus antigens. Antigenic analyses revealed consistent differences between isolates whose natural hosts were dogs and those of haematophagous bats, often isolated from cattle. Three out of four isolates from horses and one from a domestic dog showed patterns of reactivity found only in viruses of insectivorous bats, indicating that non-haematophagous bats do play a unique role in the transmission of the virus to other species.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Rabies virus
/
Antigenic Variation
/
Antibodies, Monoclonal
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
Portuguese
Journal:
Arq. bras. med. vet. zootec
Journal subject:
Veterinary Medicine
Year:
2008
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro de Pesquisas Veterinárias Desidério Finamor/BR
/
Embrapa Suínos e Aves/BR
/
Secretaria Estadual da Saúde/BR
/
Secretaria de Saúde do Distrito Federal/BR
/
Universidade Federal do Rio Grande do Sul/BR
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