Atividade in vitro do óleo essencial de Origanum vulgare frente à Sporothrix Schenckii / In vitro activity of the essential oil of Origanum vulgare against Sporothrix schenckii
Arq. bras. med. vet. zootec
;
60(2): 513-516, abr. 2008. graf
Article
in Portuguese
| LILACS
| ID: lil-484686
ABSTRACT
In vitro activity of the essential oil Origanum vulgare against Sporothrix schenckii was determined by the MIC (Minimum Inhibitory Concentration). For this, seven samples of S. schenckii were studied, two isolated from two cases of human sporotrichosis and five isolated from cats. Analysis of the essential oil was carried out in a gas chromatograph (GC/FID) for the identification and quantification of thymol and carvacrol (antifungal agents). MIC was obtained based on the microdilution method according to the adapted document NCCLS-M 27A2 for fitopharmacy. All the isolates presented sensibility to the essential oil. S. schenckii was inhibited in a concentration of 0.25 percent (250m l/ml). Chromatographic analysis showed that thymol concentration was bigger than carvacrol. The antifungal activity demonstrated by the essential oil of O. vulgare against S. Schenckii stimulates the accomplishment of more studies, including in vivo studies.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Sporotrichosis
/
Sporothrix
/
Oils, Volatile
/
Origanum
Type of study:
Prognostic study
Limits:
Animals
Language:
Portuguese
Journal:
Arq. bras. med. vet. zootec
Journal subject:
Veterinary Medicine
Year:
2008
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
UFRGS/BR
/
Universidade Federal de Pelotas/BR
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