Hipertensión arterial resistente: [revisión] / Resistant hypertension: [review]
Rev. méd. Chile
;
136(4): 528-538, abr. 2008. ilus, tab
Article
in Spanish
| LILACS
| ID: lil-484930
ABSTRACT
Resistant hypertension, defined as a persistent blood pressure over 140/90 mmHg despite the use of three antihypertensive drugs including a diuretic, is unusual. The diagnosis requires ruling out initially pseudoresistance and a lack of compliance with treatment. Ambulatory blood pressure recording allow the recognition of white coat hypertension. When there is a clinical or laboratory suspicion, secondary causes of hypertension should be discarded. Excessive salt intake, the presence of concomitant diseases such as diabetes mellitus, chronic renal disease, obesity, and psychiatric conditions such as panic attacks, anxiety and depression, should also be sought. The presence of target organ damage requires a more aggressive treatment of hypertension. Recent clinical studies indicate that the administration of aldosterone antagonists as a fourth therapeutic line provides significant additional blood pressure reduction, when added to previous antihypertensive regimens in subjects with resistant hypertension. The possible blood pressure lowering effects of prolonged electrical activation of carotid baroreceptors is under investigation.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Drug Resistance
/
Hypertension
Type of study:
Diagnostic study
/
Etiology study
Limits:
Humans
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2008
Type:
Article
Affiliation country:
Argentina
Institution/Affiliation country:
UBA/AR
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