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Seroprevalence of NMO-IgG antibody in Brazilian patients with neuromyelitis optica / Soroprevalência do anticorpo NMO-IgG em pacientes brasileiros com neuromielite óptica
Adoni, Tarso; Lino, Angelina Maria Martins; Marchiori, Paulo Eurípedes; Kok, Fernando; Callegaro, Dagoberto.
  • Adoni, Tarso; University of São Paulo. School of Medicine. Department of Neurology. São Paulo. BR
  • Lino, Angelina Maria Martins; University of São Paulo. School of Medicine. Department of Neurology. São Paulo. BR
  • Marchiori, Paulo Eurípedes; University of São Paulo. School of Medicine. Department of Neurology. São Paulo. BR
  • Kok, Fernando; University of São Paulo. School of Medicine. Department of Neurology. São Paulo. BR
  • Callegaro, Dagoberto; University of São Paulo. School of Medicine. Department of Neurology. São Paulo. BR
Arq. neuropsiquiatr ; 66(2b): 295-297, jun. 2008. tab
Article in English | LILACS | ID: lil-486179
ABSTRACT
OBJECTIVE: To determine the seroprevalence of neuromyelitis optica antibody (NMO)-IgG in Brazilian patients with clinical diagnosis of relapsing neuromyelitis optica, also known as Devic's disease. METHOD: We determined NMO-IgG titers in 28 patients (25 of them females) that fulfilled the 1999 NMO diagnostic criteria proposed by Wingerchuk et al. RESULTS: NMO-IgG was detected in 18 NMO patients (64.3 percent). CONCLUSION: Our results showed that seroprevalence of NMO-IgG in Brazilian NMO patients was similar to the observed in other studies.
RESUMO
OBJETIVO: Determinar a soroprevalência do anticorpo neuromielite óptica (NMO)-IgG em pacientes brasileiros com diagnóstico de neuromielite óptica recorrente, também conhecida como doença de Devic. MÉTODO: Nós pesquisamos a presença do anticorpo NMO-IgG em 28 pacientes (25 do sexo feminino) que preenchiam os critérios diagnósticos para NMO propostos por Wingerchuk et al. em 1999. RESULTADOS: Dezoito pacientes (64,3 por cento) apresentaram a pesquisa positiva do NMO-IgG. CONCLUSÃO: Nossos resultados demonstraram que a soroprevalência do anticorpo NMO-IgG em pacientes brasileiros com NMO é semelhante àquela encontrada em outros estudos.
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Full text: Available Index: LILACS (Americas) Main subject: Autoantibodies / Immunoglobulin G / Neuromyelitis Optica Limits: Adolescent / Adult / Child / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2008 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Autoantibodies / Immunoglobulin G / Neuromyelitis Optica Limits: Adolescent / Adult / Child / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2008 Type: Article Affiliation country: Brazil Institution/Affiliation country: University of São Paulo/BR