Lectin staining patterns in human gastric mucosae with and without exposure to Helicobacter pylori / Padrões de ligação de lectinas em mucosa gástrica humana com e sem exposição a Helicobacter pylori
Braz. j. microbiol
;
39(2): 238-240, Apr.-June 2008. tab
Article
in English
| LILACS
| ID: lil-487697
ABSTRACT
The aim of the present study was to evaluate qualitative changes in the glycoconjugate expression in human gastric tissue of positive and negative patients for Helicobacter pylori, through lectins: Wheat Germ Agglutinin (WGA) and Concanavalin A (Con A). The lectins recognized differently the glycoconjugates in the superficial mucous layer at the gastric tissues. The results suggest a significant change in the carbohydrate moieties present on the surface of the gastric cells during infection.
RESUMO
O objetivo do presente estudo foi avaliar as mudanças qualitativas na expressão de glicoconjugados em tecidos gástrico humano de pacientes infectados ou não pelo Helicobacter pylori, através das lectinas: Wheat germ agglutinin (WGA) e Concanavalina A (Con A). As lectinas reconheceram diferentemente os glicoconjugados nas camadas mucosas superficiais do tecido gástrico. Os resultados sugerem mudanças significantes nas porções de carboidratos presentes nas células gástricas durante a infecção.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
In Vitro Techniques
/
Glycoconjugates
/
Helicobacter pylori
/
Helicobacter Infections
/
Gastric Mucosa
/
Lectins
Type of study:
Evaluation studies
/
Qualitative research
Limits:
Humans
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2008
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal de Pernambuco/BR
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