In vitro anti-microbial activity of the Cuban medicinal plants Simarouba glauca DC, Melaleuca leucadendron L and Artemisia absinthium L
Mem. Inst. Oswaldo Cruz
;
103(6): 615-618, Sept. 2008. tab
Article
in English
| LILACS
| ID: lil-495740
ABSTRACT
In the present study, an extensive in vitro antimicrobial profiling was performed for three medicinal plants grown in Cuba, namely Simarouba glauca, Melaleuca leucadendron and Artemisia absinthium. Ethanol extracts were tested for their antiprotozoal potential against Trypanosoma b. brucei, Trypanosoma cruzi, Leishmania infantum and Plasmodium falciparum. Antifungal activities were evaluated against Microsporum canis and Candida albicans whereas Escherichia coli and Staphylococcus aureus were used as test organisms for antibacterial activity. Cytotoxicity was assessed against human MRC-5 cells. Only M. leucadendron extract showed selective activity against microorganisms tested. Although S. glauca exhibited strong activity against all protozoa, it must be considered non-specific. The value of integrated evaluation of extracts with particular reference to selectivity is discussed.
Full text:
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Index:
LILACS (Americas)
Main subject:
Plant Extracts
/
Artemisia absinthium
/
Melaleuca
/
Simarouba
/
Anti-Infective Agents
Limits:
Animals
/
Humans
Country/Region as subject:
Caribbean
/
Cuba
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2008
Type:
Article
Affiliation country:
Belgium
/
Cuba
Institution/Affiliation country:
Instituto de Medicina Tropical Pedro Kourí/CU
/
Universidad de La Habana/CU
/
University of Antwerp/BE
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