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In vitro anti-microbial activity of the Cuban medicinal plants Simarouba glauca DC, Melaleuca leucadendron L and Artemisia absinthium L
Fernández-Calienes Valdés, Aymé; Mendiola Martínez, Judith; Scull Lizama, Ramón; Vermeersch, Marieke; Cos, Paul; Maes, Louis.
  • Fernández-Calienes Valdés, Aymé; Instituto de Medicina Tropical Pedro Kourí. Departamento de Parasitología. La Habana. CU
  • Mendiola Martínez, Judith; Instituto de Medicina Tropical Pedro Kourí. Departamento de Parasitología. La Habana. CU
  • Scull Lizama, Ramón; Universidad de La Habana. Instituto de Farmacia y Alimentos. Departamento de Farmacia. La Habana. CU
  • Vermeersch, Marieke; University of Antwerp. Laboratory for Microbiology, Parasitology and Hygiene. Antwerp. BE
  • Cos, Paul; University of Antwerp. Laboratory for Microbiology, Parasitology and Hygiene. Antwerp. BE
  • Maes, Louis; University of Antwerp. Laboratory for Microbiology, Parasitology and Hygiene. Antwerp. BE
Mem. Inst. Oswaldo Cruz ; 103(6): 615-618, Sept. 2008. tab
Article in English | LILACS | ID: lil-495740
Responsible library: BR1.1
ABSTRACT
In the present study, an extensive in vitro antimicrobial profiling was performed for three medicinal plants grown in Cuba, namely Simarouba glauca, Melaleuca leucadendron and Artemisia absinthium. Ethanol extracts were tested for their antiprotozoal potential against Trypanosoma b. brucei, Trypanosoma cruzi, Leishmania infantum and Plasmodium falciparum. Antifungal activities were evaluated against Microsporum canis and Candida albicans whereas Escherichia coli and Staphylococcus aureus were used as test organisms for antibacterial activity. Cytotoxicity was assessed against human MRC-5 cells. Only M. leucadendron extract showed selective activity against microorganisms tested. Although S. glauca exhibited strong activity against all protozoa, it must be considered non-specific. The value of integrated evaluation of extracts with particular reference to selectivity is discussed.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Plant Extracts / Artemisia absinthium / Melaleuca / Simarouba / Anti-Infective Agents Limits: Animals / Humans Country/Region as subject: Caribbean / Cuba Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2008 Type: Article Affiliation country: Belgium / Cuba Institution/Affiliation country: Instituto de Medicina Tropical Pedro Kourí/CU / Universidad de La Habana/CU / University of Antwerp/BE

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Full text: Available Index: LILACS (Americas) Main subject: Plant Extracts / Artemisia absinthium / Melaleuca / Simarouba / Anti-Infective Agents Limits: Animals / Humans Country/Region as subject: Caribbean / Cuba Language: English Journal: Mem. Inst. Oswaldo Cruz Journal subject: Tropical Medicine / Parasitology Year: 2008 Type: Article Affiliation country: Belgium / Cuba Institution/Affiliation country: Instituto de Medicina Tropical Pedro Kourí/CU / Universidad de La Habana/CU / University of Antwerp/BE