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Influence of medium constituents on the biosynthesis of cephalosporin-C
Nigam, Vinod Kumar; Verma, Ruchi; Kumar, Abhishek; Kundu, Subir; Ghosh, Purnendu.
  • Nigam, Vinod Kumar; Birla Institute of Scientific Research Statue Circle. Jaipur. IN
  • Verma, Ruchi; Birla Institute of Scientific Research Statue Circle. Jaipur. IN
  • Kumar, Abhishek; Birla Institute of Scientific Research Statue Circle. Jaipur. IN
  • Kundu, Subir; Banaras Hindu University. Institute of Technology. School of Biochemical Engineering. Varanasi. IN
  • Ghosh, Purnendu; Birla Institute of Scientific Research Statue Circle. Jaipur. IN
Electron. j. biotechnol ; 10(2): 230-239, Apr. 15, 2007. graf, tab
Article in English | LILACS | ID: lil-499178
ABSTRACT
Acremonium chrysogenum NCIM 1069 was used for the biosynthesis of cephalosporin-C (CPC) in batch mode of cultivation. The effect of different medium constituents for better yield of CPC was thoroughly investigated. From the results of the fermentation, it was found that ammonium sulphate as inorganic nitrogen source and methionine at the concentration of 0.4 percent are most suitable for higher yield of antibiotic. The variation in the C/N ratio on the biosynthesis of CPC showed that a C/N ratio of 8.0 is most suitable for maximum production of CPC
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Full text: Available Index: LILACS (Americas) Main subject: Acremonium / Cephalosporins Language: English Journal: Electron. j. biotechnol Journal subject: Biotechnology Year: 2007 Type: Article Affiliation country: India Institution/Affiliation country: Banaras Hindu University/IN / Birla Institute of Scientific Research Statue Circle/IN

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Full text: Available Index: LILACS (Americas) Main subject: Acremonium / Cephalosporins Language: English Journal: Electron. j. biotechnol Journal subject: Biotechnology Year: 2007 Type: Article Affiliation country: India Institution/Affiliation country: Banaras Hindu University/IN / Birla Institute of Scientific Research Statue Circle/IN