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Combining functional scales and cognitive tests in screening for mild cognitive impairment at a university-based memory clinic in Brazil / Combinação de escalas funcionais e testes cognitivos para rastreio de comprometimento cognitivo leve em ambulatório universitário de memória no Brasil
Abreu, Izabella Dutra de; Nunes, Paula Villela; Diniz, Breno Satler; Forlenza, Orestes Vicente.
  • Abreu, Izabella Dutra de; Universidade de São Paulo. School of Medicine. Department of Psychiatry. Laboratory of Neuroscience. Memory Clinic. São Paulo. BR
  • Nunes, Paula Villela; Universidade de São Paulo. School of Medicine. Department of Psychiatry. Laboratory of Neuroscience. Memory Clinic. São Paulo. BR
  • Diniz, Breno Satler; Universidade de São Paulo. School of Medicine. Department of Psychiatry. Laboratory of Neuroscience. Memory Clinic. São Paulo. BR
  • Forlenza, Orestes Vicente; Universidade de São Paulo. School of Medicine. Department of Psychiatry. Laboratory of Neuroscience. Memory Clinic. São Paulo. BR
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; 30(4): 346-349, Dec. 2008. tab
Article in English | LILACS | ID: lil-501865
ABSTRACT
OBJECTIVE: To determine the diagnostic accuracy of the Mini-Mental State Examination combined to the Informant Questionnaire on Cognitive Decline in the Elderly for the identification of mild cognitive impairment. METHOD: 191 elderly subjects were assessed with the Mini-Mental State Examination, and their informants were assessed with the Informant Questionnaire on Cognitive Decline in the Elderly. Subjects were divided into three groups according to their cognitive state (controls: n = 67, mild cognitive impairment: n = 65 and dementia: n = 59), which was ascertained by clinical and neuropsychological evaluation. The diagnostic accuracy of each test in the discrimination of diagnostic groups (mild cognitive impairment vs. controls, mild cognitive impairment vs. dementia and dementia vs. controls) was examined with the aid of ROC curves. We additionally verified if the combination of both tests would increase diagnostic accuracy for mild cognitive impairment and control identification. RESULTS: The combination of the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly scores did not increase the Mini-Mental State Examination diagnostic accuracy in the identification of patients with mild cognitive impairment. CONCLUSIONS: The present data do not warrant the combination of the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly as a sufficient diagnostic tool in the diagnostic screening for mild cognitive impairment.
RESUMO
OBJETIVO: Avaliar a acurácia diagnóstica do Mini-Exame do Estado Mental combinado ao Questionário do Informante sobre Declínio Cognitivo na identificação de casos de comprometimento cognitivo leve. MÉTODO: 191 indivíduos idosos foram avaliados com o Mini-Exame do Estado Mental e seus informantes com o Questionário do Informante sobre Declínio Cognitivo. Os indivíduos foram divididos em três grupos de acordo com o estado cognitivo (controles: n = 67; comprometimento cognitivo leve: n = 65; demência: n = 59), segundo avaliação clínica e neuropsicológica. Pela análise de curvas ROC, avaliamos a acurácia diagnóstica de cada teste para diferenciar os grupos diagnósticos (comprometimento cognitivo leve vs. controles; comprometimento cognitivo leve vs. demência; demência vs. controles). Adicionalmente, verificamos se a combinação dos dois testes fortalece a acurácia diagnóstica para a separação dos casos de comprometimento cognitivo leve dos controles normais. RESULTADOS: A análise combinada do Questionário do Informante sobre Declínio Cognitivo e Mini-Exame do Estado Mental não aumentou a acurácia diagnóstica do Mini-Exame do Estado Mental em predizer a ocorrência de comprometimento cognitivo leve. CONCLUSÕES: Os dados deste estudo não sustentam a utilidade clínica da combinação dos escores do Mini-Exame do Estado Mental e do Questionário do Informante sobre Declínio Cognitivo no rastreio diagnóstico do comprometimento cognitivo leve.
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Full text: Available Index: LILACS (Americas) Main subject: Cognition Disorders / Dementia / Mental Status Schedule / Neuropsychological Tests Type of study: Diagnostic study / Prognostic study / Screening study Limits: Aged / Humans Country/Region as subject: South America / Brazil Language: English Journal: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Journal subject: Psychiatry Year: 2008 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de São Paulo/BR

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Full text: Available Index: LILACS (Americas) Main subject: Cognition Disorders / Dementia / Mental Status Schedule / Neuropsychological Tests Type of study: Diagnostic study / Prognostic study / Screening study Limits: Aged / Humans Country/Region as subject: South America / Brazil Language: English Journal: Braz. J. Psychiatry (São Paulo, 1999, Impr.) Journal subject: Psychiatry Year: 2008 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de São Paulo/BR