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Oral candidiasis in HIV+ patients under treatment with protease inhibitors
Witzel, Andréa Lusvarghi; Silveira, Fernando Ricardo Xavier da; Pires, Maria de Fátima Costa; Lotufo, Mônica Andrade.
  • Witzel, Andréa Lusvarghi; University of São Paulo. School of Dentistry. Department of Stomatology.
  • Silveira, Fernando Ricardo Xavier da; University of São Paulo. School of Dentistry. Department of Stomatology.
  • Pires, Maria de Fátima Costa; Adolfo Lutz Institute. São Paulo. BR
  • Lotufo, Mônica Andrade; Ibirapuera University. Dental School.
Braz. oral res ; 22(4): 371-377, 2008. tab
Article in English | LILACS | ID: lil-502193
ABSTRACT
The purpose of this work was to evaluate the influence of Protease Inhibitors (PI) on the occurrence of oral candidiasis in 111 HIV+ patients under PI therapy (Group A). The controls consisted of 56 patients that were not using PI drugs (Group B) and 26 patients that were not using any drugs for HIV therapy (Group C). The patient's cd4 cell counts were taken in account for the correlations. One hundred and ninety three patients were evaluated. The PI did not affect the prevalence of oral candidiasis (p = 0.158) or the frequency of C. albicans isolates (p = 0.133). Patients with lower cd4 cell counts showed a higher frequency of C. albicans isolates (p = 0.046) and a greater occurrence of oral candidiasis (p = 0.036).
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Antiviral Agents / Candida albicans / Candidiasis, Oral / HIV Protease Inhibitors / AIDS-Related Opportunistic Infections / Mouth Mucosa Type of study: Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. oral res Journal subject: Dentistry Year: 2008 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Adolfo Lutz Institute/BR

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Full text: Available Index: LILACS (Americas) Main subject: Antiviral Agents / Candida albicans / Candidiasis, Oral / HIV Protease Inhibitors / AIDS-Related Opportunistic Infections / Mouth Mucosa Type of study: Risk factors Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. oral res Journal subject: Dentistry Year: 2008 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Adolfo Lutz Institute/BR