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Valores normales de captación de 131Yodo de 2 y 24 horas / Normal 131Iodine uptake values at 2 ano 24 hours
González E, Patricio; Carmona C, Alberto R; Araya Q, Verónica; Miranda F, Karina; Massardo V, Teresa; Jiménez R, Beatriz; Jaimovich F, Rodrigo; Gatica R, Héctor.
  • González E, Patricio; Universidad de Chile. Hospital Clínico. Departamento de Medicina. Sección de Medicina Nuclear.
  • Carmona C, Alberto R; Universidad de Chile. Hospital Clínico. Departamento de Medicina. Sección de Medicina Nuclear.
  • Araya Q, Verónica; Universidad de Chile. Hospital Clínico. Departamento de Medicina. Sección de Endocrinología.
  • Miranda F, Karina; Programa Organismo Internacional de Energía Atómica.
  • Massardo V, Teresa; Universidad de Chile. Hospital Clínico. Departamento de Medicina. Sección de Medicina Nuclear.
  • Jiménez R, Beatriz; Universidad de Chile. Hospital Clínico. Departamento de Medicina. Sección de Endocrinología.
  • Jaimovich F, Rodrigo; Universidad de Chile. Hospital Clínico. Departamento de Medicina. Sección de Medicina Nuclear.
  • Gatica R, Héctor; Universidad de Chile. Hospital Clínico. Unidad de Epidemiología. Santiago de Chile. CL
Rev. méd. Chile ; 136(10): 1288-1293, Oct. 2008. tab
Article in Spanish | LILACS | ID: lil-503896
ABSTRACT

Background:

Radiolabeled iodine uptake is a useful tool in the study of thyroid diseases.

Aim:

To obtain normal values for 131 Iodine thyroid uptake in healthy volunteers. Material and

methods:

A total of 105 subjects were included (52 males and 53 females), with a mean age of 45 years (range 20 to 68, evenly distributed in decades). A questionnaire was applied and a clinical examination was performed to rule out endocrine diseases. Serum TSH and anti-thyroperoxidase antibodies were also measured. The oral 131I dose was 5-10 fiCi, and a Thyrad equipment was used for measurements at 2 and 24 h.

Results:

Mean global iodine uptake was 5.5 percent±1.8 percent (range 2.3-12.0) at 2 h and 16.2±4.8 percent (range 6.5-30.1) at 24 h. The values at 2 h among women and men were 6.0±1.8 and 4.9±1.6 percent, respectively, (p <0.02). At 24 h, the figures were 17.3±4.5 and 15.0±4.9 percent, respectively (p =0.01). Compared to their younger counterparts, radioactive iodine uptake was lower among volunteers older than 40 years, at 2 h (5.0±1.7 and 6.0±1.8, respectively, p <0.02) and at 24 h (14.9±4.4 and 17.6±4.9 percent, respectively, p <0.01).

Conclusions:

Normal thyroid uptake values in adults are influenced bygender and age. Normal thyroid iodine uptake values are slightly higher in females. Iodine thyroid uptake values decrease slightly in subjects aged more than 40years.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Thyroid Diseases / Thyroid Gland / Thyrotropin / Iodine Radioisotopes Type of study: Observational study Limits: Adult / Aged / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2008 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL

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Full text: Available Index: LILACS (Americas) Main subject: Thyroid Diseases / Thyroid Gland / Thyrotropin / Iodine Radioisotopes Type of study: Observational study Limits: Adult / Aged / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2008 Type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL