Polymorphisms on SSC15q21-q26 Containing QTL for reproduction in Swine and its association with litter size
Genet. mol. biol
;
32(1): 69-74, 2009. tab
Article
in English
| LILACS
| ID: lil-505782
ABSTRACT
Several quantitative trait loci (QTL) for important reproductive traits (ovulation rate) have been identified on the porcine chromosome 15 (SSC15). To assist in the selection of positional candidate swine genes for these QTL on SSC15, twenty-one genes had already been assigned to SSC15 in a previous study in our lab, by using the radiation hybrid panel IMpRH. Further polymorphism studies were carried out on these positional candidate genes with four breeds of pigs (Duroc, Erhualian, Dahuabai and Landrace) harboring significant differences in reproduction traits. A total of nineteen polymorphisms were found in 21 genes. Among these, seven in six genes were used for association studies, whereby NRP2 polymorphism was found to be significantly (p < 0.05) associated with litter-size traits. NRP2 might be a candidate gene for pig-litter size based on its chromosome location (Du et al., 2006), significant association with litter-size traits and relationships with Sema and the VEGF super families.
Full text:
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Index:
LILACS (Americas)
Main subject:
Swine
/
Quantitative Trait Loci
Type of study:
Prognostic study
/
Risk factors
Limits:
Animals
Language:
English
Journal:
Genet. mol. biol
Journal subject:
Genetics
Year:
2009
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
South China Agricultural University/CN
/
South China University of Technology/CN
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