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Effect of bicarbonate on fluoride reactivity with enamel / Efeito do bicarbonato na reatividade do fluoreto com esmalte
Peres, Paulo Edelvar C; Santos, Denis C. L; Tabchoury, Cínthia Pereira Machado; Cury, Jaime Aparecido.
  • Peres, Paulo Edelvar C; Federal University of Santa Maria. Faculty of Dentistry. Santa Maria. BR
  • Santos, Denis C. L; UNICAMP. Piracicaba Dental School. Piracicaba. BR
  • Tabchoury, Cínthia Pereira Machado; UNICAMP. Piracicaba Dental School. Piracicaba. BR
  • Cury, Jaime Aparecido; UNICAMP. Piracicaba Dental School. Piracicaba. BR
Rev. odonto ciênc ; 24(1): 6-9, jan.-mar. 2009. graf, tab
Article in English | LILACS, BBO | ID: lil-506367
ABSTRACT

Purpose:

Bicarbonate (HCO-3) is an alkaline and buffering substance found in dentifrices, which could improve the anti-caries effect of fluoride (F). However, HCO-3 could reduce the formation of calcium fluoride-like (CaF2), the most important product of F reactivity with enamel, whose formation is higher in low pH. The aim of this in vitro study was to evaluate if HCO-3 interferes with the reactivity of F with human enamel.

Methods:

Five dentifrice formulations were evaluated placebo of F and HCO-3 (pH 7.0); HCO-3 (pH 9.0); F (pH 7.0); F (pH 9.0) and F+HCO-3 (pH 9.0). F dentifrices contained NaF and all dentifrices were silica-based. The concentrations of total F (TF), CaF2 and firmly bound F (FA, fluorapatite-like) formed in enamel after 1-min reaction with dentifrice slurries (13) were determined.

Results:

The formation of TF, CaF2 and FA was reduced in 22.1 %, 47.9 % and 4.8 %, respectively, by the presence of HCO-3 in the dentifrice formulation.

Conclusion:

This in vitro data suggest that addition of HCO-3 to a dentifrice may interfere with the reactivity of F with enamel, reducing mainly the concentration of CaF2 formed.
RESUMO

Objetivo:

O bicarbonato (HCO-3 ) é uma substância alcalina e tamponante encontrada em dentifrícios, que poderia melhorar o efeito anticárie do fluoreto (F). No entanto, HCO-3 poderia reduzir a formação de fluoreto de cálcio (CaF2), o mais importante produto da reatividade do F com esmalte, cuja formação é maior em baixo pH. O objetivo deste estudo foi avaliar in vitro se o HCO-3 interfere na reatividade do F com o esmalte humano.

Metodologia:

Cinco formulações de dentifrícios foram avaliadas placebo de F e HCO-3(pH 7,0); HCO-3 (pH 9,0); F (pH 7,0); F (pH 9,0) e F+HCO-3 (pH 9,0). Os dentifrícios fluoretados continham NaF e todos continham sílica como abrasivo. As concentrações de F total (FT), CaF2 e F firmemente ligado (FA, tipo flúorapatita) formadas no esmalte após 1 minuto de reação com as suspensões dos dentifrícios (13) foram determinadas.

Resultados:

A formação de FT, CaF2 e FA foram reduzidas em 22,1 %; 47,9 % e 4,8 %, respectivamente, pela presença de HCO-3 na formulação do dentifrício.

Conclusão:

Os resultados in vitro sugerem que a adição de HCO-3 a um dentifrício pode interferir com a reatividade do F com o esmalte, principalmente reduzindo a concentração de CaF2 formado no esmalte.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Bicarbonates / In Vitro Techniques / Dental Enamel / Fluorides Type of study: Controlled clinical trial / Evaluation studies Limits: Humans Language: English Journal: Rev. odonto ciênc Journal subject: Dentistry Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Santa Maria/BR / UNICAMP/BR

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Full text: Available Index: LILACS (Americas) Main subject: Bicarbonates / In Vitro Techniques / Dental Enamel / Fluorides Type of study: Controlled clinical trial / Evaluation studies Limits: Humans Language: English Journal: Rev. odonto ciênc Journal subject: Dentistry Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Federal University of Santa Maria/BR / UNICAMP/BR