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Does group B streptococcal infection contribute significantly to neonatal sepsis in Antigua and Barbuda?
Martin, T. C; Adamson, J; Dickson, T; DiGiantomasso, E; Nesbitt, C.
  • Martin, T. C; Holberton Hospital. Paediatric Service. St John's. AG
  • Adamson, J; John Hunter Hospital. Neonatology Service and Micro-biology and Infectious Disease Service. Paediatric Service. Newcastle. AU
  • Dickson, T; John Hunter Hospital. Neonatology Service and Micro-biology and Infectious Disease Service. Paediatric Service. Newcastle. AU
  • DiGiantomasso, E; John Hunter Hospital. Neonatology Service and Micro-biology and Infectious Disease Service. Paediatric Service. Newcastle. AU
  • Nesbitt, C; Holberton Hospital. Infection Control Committee. St John's. AG
West Indian med. j ; 56(6): 498-501, Dec. 2007.
Article in English | LILACS | ID: lil-507258
ABSTRACT
Group B streptococcus is the most common cause of neonatal sepsis in the United States of America (USA). This study was undertaken to determine the contribution of group B streptococcus to neonatal septicaemia in Antigua and Barbuda. From 1994 to 2002, there were about 12 000 births, with 2500Special Care Nursery admissions, 1100 (44%) with potential neonatal septicaemia. Blood cultures were done in 433/1100 (39%) and cerebrospinal fluid cultures in 52/1100 (5%). Positive cultures were seen in 41/433 (9.5%) with group B streptococcus in 1/41 (2.4%), streptococcus “species” in 3/41 (7.4%) and positive cerebrospinal fluid cultures were seen in 2/52 (one group B streptococcus) giving 5 per 12 000 or 0.4 cases per 1000 babies. Vaginal cultures from 1994 to 2002 revealed group B streptococcus in 14/163 (8.6%) of positive bacterial cultures. A sample of pregnant women from a private office had positive culture for group B streptococcus in 2/120 (1.7%). The prevalence rate of carriage (15 to 40%) and infection (1.7 to 4 per 1000 babies) was much higher in the USA in the same period. Universal screening of mothers for group B streptococcus may not be as necessary or cost-effective inAntigua and Barbuda.
RESUMEN
Los estreptococos del grupo B son la causa más común de sepsis neonatal en los Estados Unidos (EE.UU.). Este estudio se llevó a cabo con el propósito de determinar en que medida los estreptococos del grupo B contribuyen a la septicemia neonatal en Antigua y Barbuda. Desde el año 1994 hasta el2002, hubo alrededor de 12000 nacimientos, con 2500 ingresos a la Guardería de Cuidados Especiales, 1100 (44%) con septicemia neonatal potencial. Se realizaron cultivos de sangre en 433/1100 (39%) y cultivos del líquido cefalorraquídeo cerebroespinal) en 52/1100 (5%). Seobservaron cultivos positivos en 41/433 (9.5%) con estreptococos B en 1/41 (2.4%), “especies“ de estreptococos en 3/41 (7.4%), y se observaron cultivos cefalorraquídeos positivos en 2/52 (1 de estreptococosdel grupo B), para 5 por 12 000 ó 0.4 casos por 1000 recién nacidos. Los cultivos vaginales desde el año 1994 al 2002 revelaron estreptococos del grupo B en 14/163 (8.6%) de los cultivosbacterianos positivos. Una muestra de mujeres embarazadas – provenientes de una oficina privada – tuvo un cultivo positivo para estreptococos del grupo B en 2/120 (1.7%). La tasa de prevalencia de portación (15 a 40%) e infección (1.7 a 4 por 1000 recién nacidos) fue mucho más alta en los EE.UU. en el mismo período. El pesquisaje universal de madres en relación con el estreptococo de grupo Bpuede no ser tan necesario o costo-efectivo en Antigua y Barbuda.
Subject(s)
Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Streptococcus agalactiae / Systemic Inflammatory Response Syndrome Type of study: Prevalence study / Risk factors Limits: Humans Country/Region as subject: Antigua and Barbuda / English Caribbean Language: English Journal: West Indian med. j Journal subject: Medicine Year: 2007 Type: Article Affiliation country: Antigua and Barbuda / Australia Institution/Affiliation country: Holberton Hospital/AG / John Hunter Hospital/AU

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Full text: Available Index: LILACS (Americas) Main subject: Streptococcal Infections / Streptococcus agalactiae / Systemic Inflammatory Response Syndrome Type of study: Prevalence study / Risk factors Limits: Humans Country/Region as subject: Antigua and Barbuda / English Caribbean Language: English Journal: West Indian med. j Journal subject: Medicine Year: 2007 Type: Article Affiliation country: Antigua and Barbuda / Australia Institution/Affiliation country: Holberton Hospital/AG / John Hunter Hospital/AU