Cytotoxicity of intraoral orthodontic elastics
Braz. j. oral sci
;
7(24): 1520-1525, jan.-mar. 2008. ilus, tab
Article
in English
| LILACS, BBO
| ID: lil-510952
ABSTRACT
Aim:
The present study compared in vitro four types of latex intraoral elastics (5/16 = 7.9 mm, mean load) regarding their possible cytotoxic effects. Material andMethods:
The sample was allocated to four groups of 24 elastics Group A (American Orthodontics), Group M (Morelli), Group T (TP Orthodontics), and Group U (Uniden). Cytotoxicity assays were performed using cell culture medium containing epithelioid-type cells (Hep-2 line) derived from human laryngeal carcinoma. Two methods for evaluating the cytotoxicity, the agar overlay test and dye-uptake test, were employed at two different moments (0 and 24 h). Data were compared by analysis of variance (ANOVA) and Tukeys test (p<0.05).Results:
The results showed statistically significant difference (p<0.05) between Groups T and M, T and U, A and M, and A and U, for dye-uptake test at 0 and 24 h. No cell lysis was found in Groups T and A for the agar overlay test, whereas 80% cell lysis was found in Groups M and U after 24 h according to the Stanfords response index (RI).Conclusion:
Both TP Orthodontics and American Orthodontics elastics evoked less cell lysis than Morelli and Uniden elastics.
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Index:
LILACS (Americas)
Main subject:
Materials Testing
/
Toxicity Tests
/
Elastomers
Language:
English
Journal:
Braz. j. oral sci
Journal subject:
Dentistry
Year:
2008
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Rio de Janeiro/BR
/
School of Pharmacy and Dentistry of Alfenas/BR
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