Pubarquia precoz: Experiencia en 173 casos / Precocious pubarche: Experience in 173 cases
Rev. méd. Chile
;
137(1): 31-38, ene. 2009. tab
Article
in Spanish
| LILACS
| ID: lil-511841
ABSTRACT
Background:
Precocious pubarche (PP), defined as the development of sexual pubic hair before 8 years of age in females and before 9 years in males, is usually a benign condition but it can also be the first sign of an underlying disease.Aim:
To analyze the etiology andperform a short term follow up in a cohort of patients with PP. Material andmethods:
A group of 173 patients (158 females) consulted for PP with a mean age of 7.4±0.1 years. These patients were followed between 15 to 60 months. Anthropometric measurements, bone age, serum levels of total testosterone, 17 OH progesterone (17 OHP) and dehydroepiandrosterone sulphate (DHEAS) were evaluated.Results:
Mean birth weight and length was 3024.1±50.5 g and 48.5±0.3 cm,respectively. Ten percent of children were small for gestational age at birth. Bone age was accelerated by 1.1±0.01 years. One hundred and twelve patients were classified as having idiopathicPP (64.7%; 105 females), 29 as central precocious puberty (16.8%; only females), 16 as exaggerated adrenarche (EA 9.2%; 13 females) and 16 as non classical adrenal hyperplasia (9.2%; 11 females).Conclusions:
PP represents a common and usually benign sign. However, 26% of cases had apathologic underlying condition. Therefore, all children with PP should be evaluated by a pediatric endocrinologist. Low birth weight was not frequent in this cohort and these patients did not show EA
Full text:
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Index:
LILACS (Americas)
Main subject:
Puberty, Precocious
/
Birth Weight
Type of study:
Diagnostic study
Limits:
Child
/
Female
/
Humans
/
Male
/
Infant, Newborn
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2009
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Clínica Santa María/CL
/
Clínica las Condes/CL
/
Universidad de Los Andes/CL
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