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Anti-arthritic potential of the plant Justicia gendarussa Burm F
Paval, Jaijesh; Kaitheri, Srinivasan Keloth; Potu, Bhagath Kumar; Govindan, Sreejith; Kumar, Raju Suresh; Narayanan, Sareesh Naduvil; Moorkoth, Sudheer.
  • Paval, Jaijesh; Melaka Manipal Medical College. Department of Anatomy. Manipal. IN
  • Kaitheri, Srinivasan Keloth; Manipal College of Pharmaceutical Science. Department of Pharmaceutical Chemistry. Manipal. IN
  • Potu, Bhagath Kumar; Kasturba Medical College. Department of Anatomy. Manipal. IN
  • Govindan, Sreejith; Melaka Manipal Medical College. Department of Microbiology. Manipal. IN
  • Kumar, Raju Suresh; Melaka Manipal Medical College. Department of Physiology. Manipal. IN
  • Narayanan, Sareesh Naduvil; Melaka Manipal Medical College. Department of Physiology. Manipal. IN
  • Moorkoth, Sudheer; Manipal College of Pharmaceutical Science. Department of Pharmaceutical Chemistry. Manipal. IN
Clinics ; 64(4): 357-362, 2009. graf, tab, ilus
Article in English | LILACS | ID: lil-511939
ABSTRACT

OBJECTIVE:

To evaluate the anti-arthritic potential of the plant Justicia gendarussa using two different rat models. MATERIALS AND

METHOD:

The anti-arthritic potential of the alcoholic extract of the plant Justicia gendarussa was evaluated using the Freund's adjuvant-induced and collagen-induced arthritic rat models. The rats were treated with the ethanolic extract of Justicia gendarussa and with standard aspirin.

RESULTS:

The ethanolic extract of Justicia gendarussa showed significant anti-arthritic activity that was statistically similar to that of aspirin. Our results suggest that the alcoholic extract of Justicia gendarussa exhibits significant anti-arthritic potential.
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Full text: Available Index: LILACS (Americas) Main subject: Arthritis, Experimental / Plant Extracts / Acanthaceae / Phytotherapy Limits: Animals Language: English Journal: Clinics Journal subject: Medicine Year: 2009 Type: Article Affiliation country: India Institution/Affiliation country: Kasturba Medical College/IN / Manipal College of Pharmaceutical Science/IN / Melaka Manipal Medical College/IN

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Full text: Available Index: LILACS (Americas) Main subject: Arthritis, Experimental / Plant Extracts / Acanthaceae / Phytotherapy Limits: Animals Language: English Journal: Clinics Journal subject: Medicine Year: 2009 Type: Article Affiliation country: India Institution/Affiliation country: Kasturba Medical College/IN / Manipal College of Pharmaceutical Science/IN / Melaka Manipal Medical College/IN