The role of fecal calprotectin in investigating inflammatory bowel diseases
Clinics
;
64(5): 421-425, 2009. tab
Article
in English
| LILACS
| ID: lil-514754
ABSTRACT
INTRODUCTION:
Invasive and non-invasive tests can be used to evaluate the activity of inflammatory bowel diseases.OBJECTIVE:
The aim of the present study was to investigate the role of fecal calprotectin in evaluating inflammatory bowel disease activity and the correlation of fecal calprotectin with the erythrocyte sedimentation rate and C reactive protein values in inflammatory bowel disease.METHOD:
Sixty-five patients affected with inflammatory bowel disease were enrolled. Twenty outpatients diagnosed with inflammatory bowel disease comprised the control group.RESULTS:
In the present study, all patients in the control group had an fecal calprotectin value lower than the cut-off point (50 mg/kg).CONCLUSION:
In conclusion, fecal calprotectin was found to be strongly associated with colorectal inflammation indicating organic disease. Fecal calprotectin is a simple and non-invasive method for assessing excretion of macrophages into the gut lumen. Fecal calprotectin values can be used to evaluate the response to treatment, to screen asymptomatic patients, and to predict inflammatory bowel disease relapses.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Inflammatory Bowel Diseases
/
Leukocyte L1 Antigen Complex
/
Feces
Type of study:
Controlled clinical trial
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2009
Type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Ankara University Hospital/TR
/
Fatih University Hospital/TR
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