The importance of serological assays in diagnosing acute pulmonary histoplasmosis
J. venom. anim. toxins incl. trop. dis
;
15(2): 278-288, 2009. ilus
Article
in English
| LILACS
| ID: lil-517286
ABSTRACT
Histoplasmosis is a systemic mycosis caused by inhalation of Histoplasma capsulatum microconidia. The disease does not normally affect immunocompetent individuals after a single, transient inhalation exposure. However, longer exposure may cause chronic or disseminated acute pulmonary infection. Herein, we report the case of a 24-year-old immunocompetent patient, who presented fever, cough and dyspnea for one month. The chest radiography revealed interstitial infiltrate and diffuse micronodules. The patient reported having had close and prolonged contact with bats. Diagnosis was confirmed by positive double immunodifusion and immunoblotting assays. She was treated with ketoconazole (400 mg) and there was complete resolution of the disease.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Histoplasmosis
/
Lung Diseases
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
J. venom. anim. toxins incl. trop. dis
Journal subject:
Toxicology
Year:
2009
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Adolfo Lutz Institute/BR
/
University of São Paulo/BR
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