Your browser doesn't support javascript.
loading
Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach / Expressão imunoistoquímica do HER-2/NEU-CERBB-2 em pacientes com adenocarcinoma do estômago
Cirne-Lima, Fernando K; Rosa, Aline de Souza; Kulczynski, Jane M. U; Mattana, Diego S; Corezolla, Kizzy; Moreira, Luis F.
  • Cirne-Lima, Fernando K; s.af
  • Rosa, Aline de Souza; s.af
  • Kulczynski, Jane M. U; s.af
  • Mattana, Diego S; s.af
  • Corezolla, Kizzy; s.af
  • Moreira, Luis F; s.af
Rev. Col. Bras. Cir ; 36(2): 131-134, mar.-abr. 2009. ilus, tab
Article in English | LILACS | ID: lil-518213
ABSTRACT

Objectives:

To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group.

Methods:

The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin–embedded tissue sections.

Results:

The immunohistochemical reaction produced by the anti-HER- 2/Neu antibody was positive in two cases (5.4%).

Conclusion:

The low prevalence of Her-2/Neu observed in these southern brazilian cases is probably due to the great number of poorly differentiated cancers in this serie.
RESUMO

Objetivo:

Determinar a prevalência do Her-2/Neu-CerbB-2 na mucosa de pacientes com adenocarcinoma de estômago em um grupo de doentes brasileiros.

Métodos:

A expressão imunoistoquímica do Her-2/Neu foi estudada em 37 amostras de tecidosfixados em formalina e embebidos em parafina.

Resultados:

A reação imunoistoquímica produzida pelo anticorpo HER-2/Neu foi positiva em dois pacientes (5.4%).

Conclusão:

A baixa prevalência Her-2/Neu observada neste grupo de pacientes é provavelmente devida ao grande número de tumores pouco diferenciados encontrados nesta série.
Subject(s)

Fulltext
Print
XML
Search on Google
Full text: Available Index: LILACS (Americas) Main subject: Stomach Neoplasms / Adenocarcinoma Type of study: Observational study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Col. Bras. Cir Journal subject: General Surgery Year: 2009 Type: Article

Similar

MEDLINE
LILACS
LIS
Fulltext
Print
XML
Search on Google
Full text: Available Index: LILACS (Americas) Main subject: Stomach Neoplasms / Adenocarcinoma Type of study: Observational study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: English Journal: Rev. Col. Bras. Cir Journal subject: General Surgery Year: 2009 Type: Article