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Chromosome instability in industrial strains of Saccharomyces cerevisiae batch cultivated under laboratory conditions
Lucena, B. T. L; Silva-Filho, E. A; Coimbra, M. R. M; Morais, J. O. F; Simões, D. A.; Morais Junior, M. A.
Affiliation
  • Lucena, B. T. L; Universidade Federal de Pernambuco. Departamento de Genética. Recife. BR
  • Silva-Filho, E. A; Universidade Federal de Pernambuco. Setor de Biologia Molecular. Recife. BR
  • Coimbra, M. R. M; Universidade Federal de Pernambuco. Departamento de Genética. Recife. BR
  • Morais, J. O. F; Universidade Federal de Pernambuco. Departamento de Antibióticos. Recife. BR
  • Simões, D. A.; Universidade Federal de Pernambuco. Setor de Biologia Molecular. Recife. BR
  • Morais Junior, M. A; Universidade Federal de Pernambuco. Departamento de Genética. Recife. BR
Genet. mol. res. (Online) ; Genet. mol. res. (Online);6(4): 1072-1084, 2007. ilus
Article in En | LILACS | ID: lil-520042
Responsible library: BR26.1
ABSTRACT
Industrial ethanol fermentation is a complex microbiological process to which yeast cells must adapt for survival. One of the mechanisms for adaptation is thought to involve chromosome rearrangements. We found that changes in chromosome banding patterns measured by pulsed-field gel electrophoresis can also be produced in laboratory media under simulated industrial conditions. Based on analysis of their generational variation, we found that these chromosome changes were specific to the genetic backgrounds of the initial strains. We conclude that chromosome rearrangements could be one of the factors involved in yeast cell adaptation to the industrial environment.
Subject(s)
Full text: 1 Index: LILACS Main subject: Saccharomyces cerevisiae / DNA, Fungal / Chromosomes, Fungal / Chromosomal Instability / Ethanol Language: En Journal: Genet. mol. res. (Online) Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2007 Type: Article
Full text: 1 Index: LILACS Main subject: Saccharomyces cerevisiae / DNA, Fungal / Chromosomes, Fungal / Chromosomal Instability / Ethanol Language: En Journal: Genet. mol. res. (Online) Journal subject: BIOLOGIA MOLECULAR / GENETICA Year: 2007 Type: Article