Structural and Functional Analysis of Giant Strong Component of Bacillus thuringiensis Metabolic Network / Análise estrutural de funcional do GSC (Giant Strong Component) da rede metabólica de Bacillus thurigiensis
Braz. j. microbiol
;
40(2): 411-416, Apr.-June 2009. ilus, graf, tab
Article
in English
| LILACS
| ID: lil-520231
ABSTRACT
The purpose of this work was to study the giant strong component (GSC) of B. thuringiensis metabolic network by structural and functional analysis. Based on so-called "bow tie" structure, we extracted and studied GSC with its functional significance. Global structural properties such as degree distribution and average path length were computed and indicated that the GSC is also a small-world and scale-free network. Furthermore, the GSC was decomposed and functional significant for metabolism of these divisions were investigated by comparing to KEGG metabolic pathways.
RESUMO
O objetivo deste trabalho foi realizar uma análise estrutural e funcional do GSC (Giant Strong Component) da rede metabólica de Bacillus thurigiensis. Baseando-se na estrutura bow-tie, o GSC foi extraído e analisado quanto ao sue significado funcional. Propriedades estruturais globais tais como grau de distribuição e tamanho médio da via metabólica foram mensuradas, concluindo-se que o GSC é também uma rede small world e scalefree. Além disso, a rede GSC foi decomposta e as divisões com significância funcional no metabolismo foram comparadas às vias metabólicas KEGG.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Bacillus thuringiensis
/
Metabolism
Language:
English
Journal:
Braz. j. microbiol
Journal subject:
Microbiology
Year:
2009
Type:
Article
/
Project document
Affiliation country:
China
Institution/Affiliation country:
East China Normal University/CN
/
Jiangnan University/CN
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