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Lagochilascaris minor: antibody production in experimentally infected mice / Lagochilascaris minor: produção de anticorpos em camundongos experimentalmente infectados
Prudente, Mariana Félix de Souza; Crespo, Adriana de Moraes Costa; Carvalhaes, Mara Silvia.
  • Prudente, Mariana Félix de Souza; Federal University of Goiás. Institute of Tropical Pathology and Public Health. Department of Microbiology, Immunology, Parasitology and Pathology. Goiânia. BR
  • Crespo, Adriana de Moraes Costa; Federal University of Goiás. Institute of Tropical Pathology and Public Health. Department of Microbiology, Immunology, Parasitology and Pathology. Goiânia. BR
  • Carvalhaes, Mara Silvia; Federal University of Goiás. Institute of Tropical Pathology and Public Health. Department of Microbiology, Immunology, Parasitology and Pathology. Goiânia. BR
Rev. Soc. Bras. Med. Trop ; 42(3): 325-328, May-June 2009. graf
Article in English | LILACS | ID: lil-522264
ABSTRACT
Lagochilascaris minor is the causative agent of lagochilascariosis, a disease that affects the neck region and causes festering abscesses, with eggs, adult parasites and L3/L4 larvae within the purulent exudates. Today, mice are considered to be intermediate hosts for the parasite. C57BL/6 mice produce immunoglobulin IgM, IgA and IgG against the crude extract of the parasite; on the other hand, antibodies produced against the secreted/excreted antigens of Lagochilascaris minor present lower levels of IgM, IgA and IgG. This is the first description of antibody detection against different antigens of Lagochilascaris minor.
RESUMO
Lagochilascaris minor é o agente etiológico da lagochilascariose, uma doença que afeta a região do pescoço causando abscessos exudativos com presença de ovos, parasitos adultos e larvas nos de exudatos purulentos. Hoje em dia, camundongos são considerados os hospedeiros intermediários para o parasita. Camundongos C57BL/6 produziram imunoglobulinas IgM, IgA e IgG contra o extrato bruto do parasita; por outro lado, anticorpos produzidos contra os antígenos secretados/excretados de Lagochilascaris minor apresentaram níveis mais baixos de IgM, IgA e IgG. Esta é a primeira descrição da detecção de anticorpos contra diferentes antígenos de Lagochilascaris minor.
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Full text: Available Index: LILACS (Americas) Main subject: Antibodies, Helminth / Antigens, Helminth / Nematoda / Nematode Infections Limits: Animals Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2009 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Federal University of Goiás/BR

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Full text: Available Index: LILACS (Americas) Main subject: Antibodies, Helminth / Antigens, Helminth / Nematoda / Nematode Infections Limits: Animals Language: English Journal: Rev. Soc. Bras. Med. Trop Journal subject: Tropical Medicine Year: 2009 Type: Article / Project document Affiliation country: Brazil Institution/Affiliation country: Federal University of Goiás/BR