Initial antimicrobial activity studies of plants of the riverside forests of the southern Uruguay River / Estudos antimicrobianos preliminares de plantas da floresta ribeirinha do sul do rio Uruguai
Rev. bras. farmacogn
;
19(1a): 20-25, Jan.-Mar. 2009. tab
Article
in English
| LILACS
| ID: lil-522414
ABSTRACT
Development of new antimicrobial compounds against different microorganisms is becoming critically important, as infectious diseases are still one of the leading causes of death in the world. Plants can be a useful source of these lead compounds. In this study, 66 extracts of 25 plants of the riverside forest of southern Uruguay River were studied for antimicrobial activity against Staphylococcus aureus, Listeria inocua, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Aspergillus niger and Candida albicans. Fifty-three of these extracts showed some kind of antimicrobial activity. Six of these (Eugenia mansoni, Eugenia repanda, Myrcianthes cisplatensis, Paullinia ellegans, Petunia sp and Ruprechtia laxiflora) presented activity against Mycobacterium tuberculosis with MIC values as low as 50 μg/mL.
RESUMO
As doenças infecciosas ainda são uma das principais causas de morte no mundo, sendo de significativa importância o desenvolvimento de novos compostos antimicrobianos contra diferentes microrganismos. As plantas podem ser uma boa fonte para direcionar a busca destes compostos. Neste estudo, 66 extratos de 25 plantas da floresta ribeirinha do sul do Rio Uruguai foram estudados para a atividade antimicrobiana contra o Staphylococcus aureus, Listeria inocua, Escherichia coli, Pseudomonas aeruginosa, Mycobacterium tuberculosis, Aspergillus niger e Candida albicans. Cinqüenta e três destes extratos apresentaram algum tipo de atividade antimicrobiana. Seis (Eugenia mansoni, Eugenia repanda, Myrcianthes cisplatensis, Paullinia ellegans, Petunia sp e Ruprechtia laxiflora) apresentaram atividade contra o Mycobacterium tuberculosis com CIM de 50 μg/mL.
Full text:
Available
Index:
LILACS (Americas)
Country/Region as subject:
South America
/
Uruguay
Language:
English
Journal:
Rev. bras. farmacogn
Journal subject:
Pharmacy
Year:
2009
Type:
Article
Affiliation country:
Brazil
/
Uruguay
Institution/Affiliation country:
Facultad de Química/UY
/
Fundação Universidade Federal do Rio Grande/BR
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