O papel atual do cirurgião no tratamento do GIST / The role of the surgeon in the management of GIST
Rev. Col. Bras. Cir
;
36(3): 261-265, jul. 2009. ilus
Article
in English, Portuguese
| LILACS
| ID: lil-522457
ABSTRACT
Recent progress in gastrointestinal stromal tumor's (GIST) treatment were responsible for changing GIST's natural history. Knowlegde acquirement of molecular mechanism-based systemic therapy gave rise to the development of targeted antineoplastic drugs capable of reaching outcomes that had never been reached before. The introduction of imatinib in the clinical practice not only changed GIST's patients survival but also shifted paradigms. However, besides all these new advances and the improved results with imatinib, the surgeon still plays a pivotal role in the management of the primary GIST tumor and even in the metastatic setting.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Gastrointestinal Stromal Tumors
Limits:
Humans
Language:
English
/
Portuguese
Journal:
Rev. Col. Bras. Cir
Journal subject:
General Surgery
Year:
2009
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
INCA/BR
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