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The rabbit as an animal model for experimental surgery / O coelho como modelo animal para cirurgia experimental
Calasans-Maia, Mônica Diuana; Monteiro, Maria Lucia; Áscoli, Fábio Oliveira; Granjeiro, José Mauro.
  • Calasans-Maia, Mônica Diuana; Fluminense Federal University. University Hospital Antonio Pedro. Cell Therapy Center. Niteroi. BR
  • Monteiro, Maria Lucia; Fluminense Federal University. School of Veterinary Medicine. Niteroi. BR
  • Áscoli, Fábio Oliveira; Oswaldo Cruz Foundation. Pharmacodynamics Department. BR
  • Granjeiro, José Mauro; Fluminense Federal University. Biology Institute. Niteroi. BR
Acta cir. bras ; 24(4): 325-328, July-Aug. 2009.
Article in English | LILACS | ID: lil-522969
ABSTRACT
The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. However, information on precautions when using this animal as an experimental model is limited. This review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. Based upon the literature and our own experience with white New Zealand rabbits, we conclude that the rabbit is an adequate model for experimental surgery.
RESUMO
O coelho branco da Nova Zelândia (Oryctolagus cuniculus) é freqüentemente utilizado como modelo em estudos in vivo. Contudo, as informações referentes aos cuidados no emprego deste animal como modelo experimental são limitadas. Esta revisão da literatura pretende rever a literatura desde a seleção do modelo animal até a sua morte, enfatizando, os procedimentos para transporte, criação, reprodução, comportamento, acomodação, anestesia e manejo dos animais, de forma a racionalizar a utilização desses animais reconhecendo as características próprias dessa espécie. Conclui-se que o coelho constitui um modelo adequado e viável para cirurgia experimental.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Rabbits / Surgical Procedures, Operative / Disease Models, Animal Type of study: Prognostic study Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fluminense Federal University/BR / Oswaldo Cruz Foundation/BR

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Full text: Available Index: LILACS (Americas) Main subject: Rabbits / Surgical Procedures, Operative / Disease Models, Animal Type of study: Prognostic study Limits: Animals Language: English Journal: Acta cir. bras Journal subject: General Surgery / Procedimentos Cir£rgicos Operat¢rios Year: 2009 Type: Article Affiliation country: Brazil Institution/Affiliation country: Fluminense Federal University/BR / Oswaldo Cruz Foundation/BR